Evidence map›Paper›PMID 29151616›Full record

ArticleMacromolecules2017

Polymeric Biomaterials: Diverse Functions Enabled by Advances in Macromolecular Chemistry.

Yingkai Liang, Linqing Li, Rebecca A Scott, Kristi L Kiick

Abstract read
In one paragraph

Article in Macromolecules, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingkai LiangDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Linqing LiDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Rebecca A ScottDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
Kristi L KiickDepartment of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.

Funding

VOLUMETRIC BREAST DENSITY ESTIMATION USING BREAST SURFACE RECONSTRUCTEDP20RR016472 · NCRR · UNIVERSITY OF DELAWARE · PI MENNELLA, PRINCY QUADROS · 2001 to 2011
$37.6M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
Highly resilient, hydrophilic bioelastomers for engineering vocal fold tissueR01DC011377 · NIDCD · UNIVERSITY OF DELAWARE · PI KIICK, KRISTI L · 2012 to 2016
$2.3M
Molecular Design of Advanced BiomaterialsP20GM103541 · NIGMS · UNIVERSITY OF DELAWARE · PI POLENOVA, TATYANA · 2012 to 2012
$2.1M
Cell Instructive Materials For Engineering Vascular GraftsR01HL108110 · NHLBI · NEMOURS CHILDREN'S HOSPITAL, DELAWARE · PI AKINS, ROBERT E · 2013 to 2016
$1.4M
Nanoscale engineering of novel erodible drug delivery matricesR01EB003172 · NIBIB · UNIVERSITY OF DELAWARE · PI FURST, ERIC M · 2003 to 2006
$1.2M
Instructive Materials for Directing Neovascularization and InflammationF32HL127983 · NHLBI · UNIVERSITY OF DELAWARE · PI SCOTT, REBECCA ANNE · 2016 to 2018
$192k
NCRR NIH HHS P20 RR016472NHLBI NIH HHS F32 HL127983NHLBI NIH HHS R01 HL108110NIBIB NIH HHS R01 EB003172NIDCD NIH HHS R01 DC011377NIGMS NIH HHS P20 GM103541NIGMS NIH HHS P30 GM110758
6 · The paper itself

Abstract

Biomaterials have been extensively used to leverage beneficial outcomes in various therapeutic applications, such as providing spatial and temporal control over the release of therapeutic agents in drug delivery as well as engineering functional tissues and promoting the healing process in tissue engineering and regenerative medicine. This perspective presents important milestones in the development of polymeric biomaterials with defined structures and properties. Contemporary studies of biomaterial design have been reviewed with focus on constructing materials with controlled structure, dynamic functionality, and biological complexity. Examples of these polymeric biomaterials enabled by advanced synthetic methodologies, dynamic chemistry/assembly strategies, and modulated cell-material interactions have been highlighted. As the field of polymeric biomaterials continues to evolve with increased sophistication, current challenges and future directions for the design and translation of these materials are also summarized.

Identifiers

PMID29151616
PMCPMC5687278

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.