Evidence map›Paper›PMID 29151500›Full record

ArticleInternal medicine (Tokyo, Japan)2018

Nonmyelomatous Ascites Resulting from the Increased Secretion of Vascular Endothelial Growth Factor in Multiple Myeloma.

Hiroaki Maki, Yasuhito Nannya, Yoichi Imai, Satoko Yamaguchi, Yasuhiko Kamikubo, Motoshi Ichikawa, Fumihiko Nakamura, Mineo Kurokawa

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroaki MakiDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Yasuhito NannyaDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Yoichi ImaiDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Satoko YamaguchiDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Yasuhiko KamikuboDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Motoshi IchikawaDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Fumihiko NakamuraDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Mineo KurokawaDepartment of Hematology & Oncology, Graduate School of Medicine, The University of Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ascites is a rare complication of multiple myeloma (MM); in most cases, the direct invasion of myeloma cells to the peritoneal cavity has been assumed to be the etiology because the effusion is usually exudative and contains a high proportion of myeloma cells. We herein report a case of MM with massive ascites containing only a small amount of myeloma cells. Instead, high levels of serum and ascitic vascular endothelial growth factor were detected. This was suggested to be a potential mechanism underlying the development of ascites.

Indexed as

Antineoplastic Agents, HormonalAscitesDexamethasoneHumansMaleMiddle AgedMultiple MyelomaVascular Endothelial Growth Factor AAntineoplastic Agents, HormonalDexamethasoneVascular Endothelial Growth Factor Aendocrinopathymonoclonal gammopathymultiple myeloma (MM)organomegalypleural effusionpolyneuropathyskin changes (POEMS) syndromevascular endothelial growth factor (VEGF)

Identifiers

PMID29151500
PMCPMC5874348

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.