Evidence map›Paper›PMID 29151281›Full record

ReviewJournal of cachexia, sarcopenia and muscle2018

Skeletal muscle performance and ageing.

Michael Tieland, Inez Trouwborst, Brian C Clark

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of cachexia, sarcopenia and muscle, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 473 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
473citing papers in PubMed, 6 pooled it
30.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06514872 completednot on this mapstarted 2019, after this paper: background citation

Prevalence and Determinants of Home Accidents Among Turkish Older Men and Women

Typeobservational_patient_registrySponsorAtaturk UniversityRan2019 to 2023Enrolled8,225ConditionsAge ProblemArmsprevalance and determinants of home accidents
NCT06666881 narecruitingnot on this mapstarted 2023, after this paper: background citation

(Health Promotion) Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in Head and Neck Cancer Patients

TypeinterventionalSponsorChang Gung Memorial HospitalRan2023 to 2027Enrolled60ConditionsHead and Neck Cancer, Skeletal MuscleArmsHIIT only, HIIT & Record of physical activities at home.
NCT07253714 nacompletednot on this mapstarted 2024, after this paper: background citation

The effect of proprioceptive exercise training on cervical proprioception, kinesiophobia, and pain catastrophizing levels in sarcopenic geriatric individuals residing in nursing homes

TypeinterventionalSponsorAtılım UniversityRan2024 to 2024Enrolled31ConditionsSarcopenia in ElderlyArmsClassic exercises, Proprioceptive exercise training
3 · Its place in the literature

Who cites it

473 citing papers in PubMed, 6 syntheses or guidelines pooled it, 850 citations in OpenAlex.

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  7. Cluster randomized trial of reablement strategies targeting sarcopenia (ReStart-S) in long-term care settings.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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413 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Michael TielandFaculty of Sports and Nutrition, Amsterdam University of Applied Sciences, Dr. Meurerlaan 8, 1067 SM, Amsterdam, the Netherlands.
Inez TrouwborstFaculty of Sports and Nutrition, Amsterdam University of Applied Sciences, Dr. Meurerlaan 8, 1067 SM, Amsterdam, the Netherlands.
Brian C ClarkOhio Musculoskeletal and Neurological Institute (OMNI), Ohio University, 250 Irvine Hall, Athens, OH 45701, USA.
Amsterdam University of Applied Sciences · NLOhio University · US

Funding

Neural mechanisms of dynapeniaR01AG044424 · NIA · OHIO UNIVERSITY ATHENS · PI CLARK, BRIAN C · 2014 to 2018
$1.4M
NIA NIH HHS R01 AG044424
6 · The paper itself

Abstract

The world population is ageing rapidly. As society ages, the incidence of physical limitations is dramatically increasing, which reduces the quality of life and increases healthcare expenditures. In western society, ~30% of the population over 55 years is confronted with moderate or severe physical limitations. These physical limitations increase the risk of falls, institutionalization, co-morbidity, and premature death. An important cause of physical limitations is the age-related loss of skeletal muscle mass, also referred to as sarcopenia. Emerging evidence, however, clearly shows that the decline in skeletal muscle mass is not the sole contributor to the decline in physical performance. For instance, the loss of muscle strength is also a strong contributor to reduced physical performance in the elderly. In addition, there is ample data to suggest that motor coordination, excitation-contraction coupling, skeletal integrity, and other factors related to the nervous, muscular, and skeletal systems are critically important for physical performance in the elderly. To better understand the loss of skeletal muscle performance with ageing, we aim to provide a broad overview on the underlying mechanisms associated with elderly skeletal muscle performance. We start with a system level discussion and continue with a discussion on the influence of lifestyle, biological, and psychosocial factors on elderly skeletal muscle performance. Developing a broad understanding of the many factors affecting elderly skeletal muscle performance has major implications for scientists, clinicians, and health professionals who are developing therapeutic interventions aiming to enhance muscle function and/or prevent mobility and physical limitations and, as such, support healthy ageing.

Indexed as

AgingHumansMuscle, SkeletalPhysical Functional PerformanceQuality of LifeSarcopeniaDynapeniaMobilityMuscle qualityPhysical performanceSarcopenia

Identifiers

PMID29151281
PMCPMC5803609
OpenAlexW2770065569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.