Evidence map›Paper›PMID 29151251›Full record

ArticleJournal of nephrology2018

Quality of life following hospitalization-associated acute kidney injury in children.

Kelsey L Richardson, R Scott Watson, Sangeeta Hingorani

Open access · greenAbstract read
In one paragraph

Article in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Tumour lysis syndrome.Nature reviews. Disease primers · 2024
    Review
  3. Article
  4. Acute kidney injury.Nature reviews. Disease primers · 2021
    Review
  5. Severe Acute Kidney Injury Is Associated With Increased Risk of Death and New Morbidity After Pediatric Septic Shock.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kelsey L RichardsonDivision of Pediatric Nephrology, Oregon Health & Science University, 707 SW Gaines Street, Portland, OR, 97239, USA. richarke@ohsu.edu.ORCID 0000-0003-3143-7726
R Scott WatsonDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, USA.
Sangeeta HingoraniDivision of Pediatric Nephrology, Department of Pediatrics, University of Washington, Seattle, USA.
Oregon Health & Science University · USSeattle Children's Hospital · USUniversity of Washington · US

Funding

Pediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5M
NIDDK NIH HHS T32 DK007662NIH HHS DK007662
6 · The paper itself

Abstract

objectivesAcute kidney injury (AKI) is common in hospitalized children. The impact of AKI following hospitalization is not fully understood, particularly the impact on health related quality of life (HRQOL). The goal of this study was to determine the relationship between hospitalization-associated AKI and HRQOL in a pediatric population. STUDY

designWe conducted a retrospective cohort study of children with hospitalization-associated AKI. Eligible children were 1-19 years old with AKI defined by kidney disease improving global outcomes (KDIGO) criteria and had at least one completed pediatric quality of life (PedsQL) 4.0 Generic Core Scale survey (N = 139). Participants completed up to three surveys to reflect baseline, admission and follow-up status. We categorized children as having mild AKI (KDIGO stage 1, N = 73) or severe AKI (KDIGO stage 2 or 3, N = 66). Mean PedsQL scores were compared by AKI group. Those with both baseline and follow-up surveys were analyzed to determine the proportion who returned to their baseline level of function within 8 weeks of discharge.

resultsChildren with mild and severe AKI had similar baseline and admission PedsQL scores. Although children with severe AKI had lower follow-up scores, the results were not statistically significant (78.9 vs. 85.8, p = 0.11). Of those with severe AKI, 48% returned to their baseline level of physical functioning by follow-up, compared to 73% with mild AKI (p = 0.05).

conclusionsThis is the first study of HRQOL following hospitalization-associated AKI. We found that children with severe AKI had depressed physical functioning after discharge when compared to children with mild AKI.

Indexed as

Quality of LifeAcute Kidney InjuryAdolescentChildChild, PreschoolComorbidityFemaleHospitalizationHumansInfantMaleRecovery of FunctionRetrospective StudiesSeverity of Illness IndexSurveys and QuestionnairesAcute kidney injury (AKI)OutcomesPediatricQuality of life (QOL)

Identifiers

PMID29151251
PMCPMC7316394
OpenAlexW2770279057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.