Evidence map›Paper›PMID 29151222›Full record

ArticleVirus genes2018

Full genome sequences are key to disclose RHDV2 emergence in the Macaronesian islands.

Ana M Lopes, Jose Blanco-Aguiar, Aaron Martín-Alonso, Manuel Leitão, Pilar Foronda, Marco Mendes, David Gonçalves, Joana Abrantes, Pedro J Esteves

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Virus genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Rabbit hemorrhagic disease virus 2, 2010-2023: a review of global detections and affected species.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. A Potential Atypical Case of Rabbit Haemorrhagic Disease in a Dwarf Rabbit.Animals : an open access journal from MDPI · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana M LopesCIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Rua Padre Armando Quintas, 4485-661, Vairão, Portugal.
Jose Blanco-AguiarCIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Rua Padre Armando Quintas, 4485-661, Vairão, Portugal.
Aaron Martín-AlonsoInstitute of Tropical Diseases and Public Health of the Canary Islands, Universidad de La Laguna, Avda. Fco. Sanchez s/n, 38203, Tenerife, Canary Islands, Spain.
Manuel LeitãoDireção Regional dos Recursos Florestais, Rua do Contador 23, 9500-050, Ponta Delgada, Açores, Portugal.
Pilar ForondaInstitute of Tropical Diseases and Public Health of the Canary Islands, Universidad de La Laguna, Avda. Fco. Sanchez s/n, 38203, Tenerife, Canary Islands, Spain.
Marco MendesQuinta Vila Passos, Instituto das Florestas e Conservação da Natureza, Rua Alferes Veiga Pestana, 15, 9054-505, Funchal, Madeira, Portugal.
David GonçalvesCIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Rua Padre Armando Quintas, 4485-661, Vairão, Portugal.
Joana AbrantesCIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Rua Padre Armando Quintas, 4485-661, Vairão, Portugal.
Pedro J EstevesCIBIO/InBio, Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus de Vairão, Rua Padre Armando Quintas, 4485-661, Vairão, Portugal. pjesteves@cibio.up.pt.

Funding

Fundação para a Ciência e a Tecnologia IF/00376/2015Fundação para a Ciência e a Tecnologia IF/01396/2013Fundação para a Ciência e a Tecnologia SFRH/BPD/115211/2016
6 · The paper itself

Abstract

A recent publication by Carvalho et al. in "Virus Genes" (June 2017) reported the presence of the new variant of rabbit hemorrhagic disease virus (RHDV2) in the two larger islands of the archipelago of Madeira. Based on the capsid protein sequence, the authors suggested that the high sequence identity, along with the short time spanning between outbreaks, points to dissemination from Porto Santo to Madeira. By including information of the full RHDV2 genome of strains from Azores, Madeira, and the Canary Islands, we confirm the results obtained by Carvalho et al., but further show that several subtypes of RHDV2 circulate in these islands: non-recombinant RHDV2 in the Canary Islands, G1/RHDV2 in Azores, Porto Santo and Madeira, and NP/RHDV2 also in Madeira. Here we conclude that RHDV2 has been independently introduced in these archipelagos, and that in Madeira at least two independent introductions must have occurred. We provide additional information on the dynamics of RHDV2 in the Macaronesian archipelagos of Azores, Madeira, and the Canary Islands and highlight the importance of analyzing RHDV2 complete genome.

Indexed as

Genetic VariationGenotypeWhole Genome SequencingAzoresCluster AnalysisHemorrhagic Disease Virus, RabbitPhylogenyPortugalSequence HomologySpainFull genomeIntroductionMacaronesian islandsRecombinationRHDV2

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.