ArticleTropical animal health and production2018
Aspergillus terreus treated rice straw suppresses methane production and enhances feed digestibility in goats.
Article in Tropical animal health and production, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Methanogens: vital but threatened members of the human microbiome?Trends in microbiology · 2026Review
- Integrated effects of diet and probiotics on rumen microbiota and host physiology in ruminants.Journal of animal science and technology · 2026Review
- Integrating Metabolomics and Genomics to Uncover the Impact of Fermented Total Mixed Ration on Heifer Growth Performance Through Host-Dependent Metabolic Pathways.Animals : an open access journal from MDPI · 2025Article
- Bioprocessing of Two Crop Residues for Animal Feeding into a High-Yield Lovastatin Feed Supplement.Animals : an open access journal from MDPI · 2022Article
- Lovastatin as a supplement to mitigate rumen methanogenesis: an overview.Journal of animal science and biotechnology · 2021Review
- Zebrafish as a Model for the Study of Lipid-Lowering Drug-Induced Myopathies.International journal of molecular sciences · 2021Review
- Selected Alternative Feed Additives Used to Manipulate the Rumen Microbiome.Animals : an open access journal from MDPI · 2021Review
- Naturally Produced Lovastatin Modifies the Histology and Proteome Profile of Goat Skeletal Muscle.Animals : an open access journal from MDPI · 2019Article
- Effect of different feeding management on the respiratory methane emission and feces-derived methane yield of goat.Journal of advanced veterinary and animal research · 2019Article
- Climate Change and Goat Production: Enteric Methane Emission and Its Mitigation.Animals : an open access journal from MDPI · 2018Review
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objectives of this study were to test the efficacy of producing lovastatin in rice straw treated with Aspergillus terreus in larger laboratory scale following the procedure previously reported and to investigate the effectiveness of the treated rice straw containing lovastatin on methane mitigation in goats. The concentration of lovastatin in the treated rice straw was 0.69 ± 0.05 g/kg dry matter (DM) rice straw. Our results showed that supplementation of lovastatin at 4.14 mg/kg BW reduced methane production by 32% while improving the DM digestibility by 13% (P < 0.05) in goats fed fermented rice straw compared to those fed untreated rice straw. Populations of total methanogens and Methanobacteriales species were significantly reduced (P < 0.05) while the population of total bacteria and Ruminococcus albus were increased in the treatment group (P < 0.05). Our results demonstrated that lovastatin in the treated rice straw acted specifically on the methanogens by inhibiting the activity of HMG-CoA reductase in the methanogens' cell membrane biosynthesis pathway and thus the growth of rumen methanogens as previously reported. This study provides a simple yet practical approach to mitigate enteric methane production particularly in the developing countries which depend heavily on the use of agro-biomass such as rice straw to feed their ruminant animals.
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Registered trials
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