Evidence map›Paper›PMID 29150673›Full record

ArticleNature communications2017

Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture.

Stefanie G Wohl, Nikolas L Jorstad, Edward M Levine, Thomas A Reh

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. meLife · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Stefanie G WohlDepartment of Biological Structure, University of Washington, Health Sciences Center, Box 357420, 1959 Pacific Street NE, Seattle, WA, 98195, USA.ORCID http://orcid.org/0000-0003-2559-7678
Nikolas L JorstadDepartment of Biological Structure, University of Washington, Health Sciences Center, Box 357420, 1959 Pacific Street NE, Seattle, WA, 98195, USA.
Edward M LevineDepartment of Ophthalmology and Visual Sciences, Vanderbilt University, Nashville, TN, 37232, USA.
Thomas A RehDepartment of Biological Structure, University of Washington, Health Sciences Center, Box 357420, 1959 Pacific Street NE, Seattle, WA, 98195, USA. tomreh@u.washington.edu.
University of Washington · USSeattle Pacific University · USVanderbilt University · US

Funding

Vision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI JAMES Bryant HURLEY · 1985 to 2026
$23.5M
Supplement to EY021482 to carry out a screen for retinal regeneration using CRISPR-Cas9 gene activation.R01EY021482 · NEI · UNIVERSITY OF WASHINGTON · PI THOMAS A REH · 2011 to 2026
$6.3M
Novel Activators of Regeneration in Muller gliaU01EY027265 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LEVINE, EDWARD M, PATTON, JAMES G. · 2016 to 2018
$2.2M
NEI NIH HHS P30 EY001730NEI NIH HHS R01 EY021482NEI NIH HHS U01 EY027265
6 · The paper itself

Abstract

To better understand the roles of microRNAs in glial function, we used a conditional deletion of Dicer1 (Dicer-CKO

Indexed as

3T3 CellsAnimalsCell MovementCells, CulturedDEAD-box RNA HelicasesEpendymoglial CellsGene Expression ProfilingHomeostasisMiceMice, KnockoutMice, TransgenicMicroRNAsMicroscopy, ConfocalNeurogliaRetinaRibonuclease IIIDEAD-box RNA HelicasesDicer1 protein, mouseMicroRNAsRibonuclease III

Identifiers

PMID29150673
PMCPMC5693933
OpenAlexW2768616301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.