Evidence map›Paper›PMID 29150604›Full record

ArticleNature communications2017

Transcriptional signature of human pro-inflammatory T

Dan Hu, Samuele Notarbartolo, Tom Croonenborghs, Bonny Patel, Ron Cialic, Tun-Hsiang Yang, Dominik Aschenbrenner, Karin M Andersson, Marco Gattorno, Minh Pham and 10 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 129 citations in OpenAlex.

  1. Review
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  4. Aiolos and Eos drive distinct human TH17 functional states.Cellular and molecular life sciences : CMLS · 2026
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  9. Pro-Inflammatory c-MetAnnals of neurology · 2026
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  10. Materiobiology in the omics era.Materials today. Bio · 2025
    Review
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  16. Review
  17. Article
  18. Reconstitution of CXCR3Annals of clinical and translational neurology · 2025
    Observational
  19. CD4Current molecular medicine · 2025
    Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 6 countries.

Dan HuAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Samuele NotarbartoloInstitute for Research in Biomedicine, Università della Svizzera italiana, via Vincenzo Vela 6, CH-6500, Bellinzona, Switzerland.ORCID http://orcid.org/0000-0001-5910-4910
Tom CroonenborghsProgram in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Bonny PatelAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Ron CialicAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Tun-Hsiang YangDepartment of Genetics, Harvard Medical School, Boston, MA, 02115, USA.
Dominik AschenbrennerInstitute for Research in Biomedicine, Università della Svizzera italiana, via Vincenzo Vela 6, CH-6500, Bellinzona, Switzerland.
Karin M AnderssonDepartment of Rheumatology and Inflammation Research, Sahlgrenska University Hospital, Gothenburg University, Box 480, 405 30, Gothenburg, Sweden.
Marco GattornoSecond Division of Pediatrics, G. Gaslini Scientific Institute, Largo Gerolamo Gaslini, 5, 16100, Genova(GE), Italy.
Minh PhamAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Pia KivisakkAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Isabelle V PierreAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Youjin LeeAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Karun KianiProgram in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Maria BokarewaDepartment of Rheumatology and Inflammation Research, Sahlgrenska University Hospital, Gothenburg University, Box 480, 405 30, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-9424-5145
Emily TjonAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Nathalie PochetProgram in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0003-1820-5656
Federica SallustoInstitute for Research in Biomedicine, Università della Svizzera italiana, via Vincenzo Vela 6, CH-6500, Bellinzona, Switzerland.
Vijay K KuchrooAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Howard L WeinerAnn Romney Center for Neurologic Diseases and Evergrande Center for Immunologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. hweiner@rics.bwh.harvard.edu.
Brigham and Women's Hospital · USSahlgrenska University Hospital · SEBroad Institute · USETH Zurich · CHHarvard University · USIstituto Giannina Gaslini · ITUniversità della Svizzera italiana · CHUniversity of Oxford · GB

Funding

Transcriptional regulations of effector and regulatory T cells in EAEP01NS076410 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI WEINER, HOWARD L · 2013 to 2017
$5.6M
European Research Council 323183NINDS NIH HHS P01 NS076410
6 · The paper itself

Abstract

We have previously reported the molecular signature of murine pathogenic T

Indexed as

Gene Expression ProfilingAdultAnimalsCells, CulturedFemaleHumansInterferon-gammaInterleukin-10MaleMiceMiddle AgedMultiple SclerosisTh17 CellsTh1 CellsInterferon-gammaInterleukin-10

Identifiers

PMID29150604
PMCPMC5693957
OpenAlexW2768663525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.