Evidence map›Paper›PMID 29150506›Full record

ArticleApplied and environmental microbiology2018

The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450.

Anu Humisto, Jouni Jokela, Liwei Liu, Matti Wahlsten, Hao Wang, Perttu Permi, João Paulo Machado, Agostinho Antunes, David P Fewer, Kaarina Sivonen

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  10. Frontiers in plant science · 2020
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  16. Single-bacterial genomics validates rich and varied specialized metabolism of uncultivatedProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Anu HumistoDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Jouni JokelaDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Liwei LiuDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Matti WahlstenDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Hao WangDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Perttu PermiProgram in Structural Biology and Biophysics, Institute of Biotechnology, University of Helsinki, Helsinki, Finland.
João Paulo MachadoCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Porto, Portugal.
Agostinho AntunesCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Porto, Portugal.
David P FewerDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland.
Kaarina SivonenDepartment of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, Helsinki, Finland kaarina.sivonen@helsinki.fi.
Biocenter Finland · FIUniversity of Helsinki · FIUniversidade do Porto · PTUniversity of Jyväskylä · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge

Indexed as

Multigene FamilyBacterial ProteinsMarine ToxinsNostocPhylogenyPolyketide SynthasesSequence Analysis, DNABacterial ProteinsMarine ToxinsPolyketide Synthasesswinholide AAnabaena“Candidatus Entotheonella”cyanobacteriahorizontal gene transferNostocpolyketidesscytophycinswinholidetrans-AT PKS

Identifiers

PMID29150506
PMCPMC5772238
OpenAlexW2770076518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.