Evidence map›Paper›PMID 29150441›Full record

ArticleThe Journal of biological chemistry2018

Co(II) and Ni(II) binding of the

Hsin-Ting Huang, Cedric E Bobst, Jeffrey S Iwig, Peter T Chivers, Igor A Kaltashov, Michael J Maroney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Regulation of a nickel tolerance operon conserved inApplied and environmental microbiology · 2025
    Article
  2. Compatibility of intracellular binding: Evolutionary design principles for metal sensors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. The requirement for cobalt in vitamin BBiochimica et biophysica acta. Molecular cell research · 2021
    Review
  5. Review
  6. Complexation of the nickel and cobalt transcriptional regulator RcnR with DNA.Acta crystallographica. Section F, Structural biology communications · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hsin-Ting HuangDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Cedric E BobstDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Jeffrey S IwigCarmot Therapeutics, Inc., San Francisco, California 94158.
Peter T ChiversDepartments of Biosciences and Chemistry, Durham University, Durham DH1 3LE, United Kingdom.
Igor A KaltashovDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003.
Michael J MaroneyDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003. Electronic address: mmaroney@chem.umass.edu.

Funding

Structural Parameters Involved in Metal RecognitionR01GM069696 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI MARONEY, MICHAEL J · 2004 to 2017
$3.3M
NIGMS NIH HHS R01 GM069696
6 · The paper itself

Abstract

RcnR, a transcriptional regulator in

Indexed as

Amino Acid SequenceBinding SitesCations, DivalentCobaltDNA, BacterialDNA-Binding ProteinsEscherichia coliEscherichia coli ProteinsMass SpectrometryNickelRepressor ProteinsStructure-Activity RelationshipTranscription FactorsCations, DivalentCobaltDNA, BacterialDNA-Binding ProteinsEscherichia coli ProteinsNickelRcnR protein, E coliRepressor ProteinsTranscription Factorshydrogen exchange mass spectrometrymetal homeostasismetal ion-protein interactionmetalloproteintranscription regulation

Identifiers

PMID29150441
PMCPMC5766909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.