Evidence map›Paper›PMID 29150440›Full record

ArticleScience immunology2017

License to kill: IFN-λ regulates antifungal activity of neutrophils.

Daniel Schnepf, Peter Staeheli

Abstract readComment
PubMed Publisher
In one paragraph

Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Targeting the Granulocytic Defense againstInternational journal of molecular sciences · 2023
    Article
  2. Article
  3. Review
  4. Meeting Overview: Interferon Lambda-Disease Impact and Therapeutic Potential.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2019
    Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Daniel SchnepfInstitute of Virology, Medical Center University of Freiburg, Freiburg, Germany.ORCID 0000-0002-7528-981X
Peter StaeheliInstitute of Virology, Medical Center University of Freiburg, Freiburg, Germany. peter.staeheli@uniklinik-freiburg.de.ORCID 0000-0001-7057-6177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-λ mediates antifungal immunity by stimulating neutrophils to generate reactive oxygen species.

Indexed as

Antifungal AgentsInterferonsImmunity, InnateInterferon LambdaNeutrophilsAntifungal AgentsInterferon LambdaInterferons

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.