SynthesisAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2017
Efficacy of bleach baths in reducing severity of atopic dermatitis: A systematic review and meta-analysis.
Synthesis in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 125 citations in OpenAlex.
- Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).Veterinary dermatology · 2025Pooled it
- What are the highest yielding search strategy terms for systematic reviews in atopic dermatitis? A systematic review.Archives of dermatological research · 2021Pooled it
- Interventions to reduce Staphylococcus aureus in the management of eczema.The Cochrane database of systematic reviews · 2019Pooled it
- Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial.Nature medicine · 2021Trial
- Apple cider vinegar soaks do not alter the skin bacterial microbiome in atopic dermatitis.PloS one · 2021Trial
- The Skin Microbiome of Patients With Atopic Dermatitis Normalizes Gradually During Treatment.Frontiers in cellular and infection microbiology · 2021Trial
- Dupilumab in Severe Atopic Dermatitis With Phosphoglucomutase 3 Deficiency.Scandinavian journal of immunology · 2026Article
- Past, Present, and Future of Sodium Hypochlorite in Dermatology: A Scoping Review.American journal of clinical dermatology · 2026Article
- Dysbiosis in the Pathogenesis of Atopic Dermatitis.The Journal of dermatology · 2026Review
- Chronic skin and systemic inflammation modulated by S100A8 and S100A9 complexes.Cell death and differentiation · 2025Article
- Climate Change and Pediatric Skin Health: Emerging Threats, Innovations, and Equity Gaps.Cureus · 2025Review
- Real-world Efficacy of Sodium Hypochlorite Body Wash in Managing Hidradenitis Suppurativa.The Journal of clinical and aesthetic dermatology · 2025Article
- The skin microbiome in dermatologic disease.Journal of the American Academy of Dermatology · 2025Review
- The Role of Skin Dysbiosis and Quorum Sensing in Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2025Review
- Environmental and behavioral mitigation strategies for patients with atopic dermatitis.JAAD international · 2024Article
- Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses.American journal of clinical dermatology · 2024Review
- Fruit vinegar as a promising source of natural anti-inflammatory agents: an up-to-date review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Review
- Adding Fuel to the Fire? The Skin Microbiome in Atopic Dermatitis.The Journal of investigative dermatology · 2024Review
- Bathing in Atopic Dermatitis in Pediatric Age: Why, How and When.Pediatric reports · 2024Review
- Pathogenic role of the staphylococcal accessory gene regulator quorum sensing system in atopic dermatitis.Frontiers in cellular and infection microbiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundBleach baths have been proposed as a treatment for decreasing the severity of atopic dermatitis (AD). However, conflicting results have been found regarding their efficacy.
objectiveTo determine the efficacy of bleach vs water baths at decreasing AD severity.
methodsWe performed a systematic review of all studies evaluating the efficacy of bleach baths for AD. Cochrane, EMBASE, GREAT, LILACS, MEDLINE, and Scopus were searched. Two authors independently performed study selection and data extraction.
resultsFive studies were included in the review. Four studies reported significantly decreased AD severity in patients treated with bleach on at least 1 time point. However, of 4 studies comparing bleach with water baths, only 2 found significantly greater decreases in AD severity with bleach baths, 1 found greater decreases with water baths, and 1 found no significant differences. In pooled analyses, there were no significant differences observed between bleach vs water baths at 4 weeks vs baseline for the Eczema Area and Severity Index (I
conclusionAlthough bleach baths are effective in decreasing AD severity, they do not appear to be more effective than water baths alone. Future larger-scale, well-designed randomized controlled trials are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.