ArticleRespiratory research2017
Electronic cigarette vapor alters the lateral structure but not tensiometric properties of calf lung surfactant.
Article in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Short halt in vaping modifies cardiorespiratory parameters and urine metabolome: a randomized trial.American journal of physiology. Lung cellular and molecular physiology · 2020Trial
- Fourth generation e-cigarette vaping induces transient lung inflammation and gas exchange disturbances: results from two randomized clinical trials.American journal of physiology. Lung cellular and molecular physiology · 2019Trial
- Exposure to Aldehyde Cherry e-Liquid Flavoring and Its Vaping Byproduct Disrupt Pulmonary Surfactant Biophysical Function.Environmental science & technology · 2024Article
- Molecular Impact of Conventional and Electronic Cigarettes on Pulmonary Surfactant.International journal of molecular sciences · 2023Review
- E-cigarette aerosol exposure of pulmonary surfactant impairs its surface tension reducing function.PloS one · 2022Article
- Revisiting the role of pulmonary surfactant in chronic inflammatory lung diseases and environmental exposure.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant.Chemical research in toxicology · 2021Article
- E-cigarette exposures, respiratory tract infections, and impaired innate immunity: a narrative review.Pediatric medicine (Hong Kong, China) · 2021Article
- An adverse outcome pathway for lung surfactant function inhibition leading to decreased lung function.Current research in toxicology · 2021Article
- The fog, the attractive and the addictive: pulmonary effects of vaping with a focus on the contribution of each major vaping liquid constituent.European respiratory review : an official journal of the European Respiratory Society · 2020Review
- Electronic-Cigarette Vehicles and Flavoring Affect Lung Function and Immune Responses in a Murine Model.International journal of molecular sciences · 2020Article
- Suggested management of e-cigarette or vaping product use associated lung injury (EVALI).Journal of thoracic disease · 2020Article
- [E-cigarettes: toxicological fiasco or better than not giving up smoking?]Der Internist · 2020Review
- Mainstream smoke constituents andToxicology reports · 2019Article
- The implications of Vitamin E acetate in E-cigarette, or vaping, product use-associated lung injury.Annals of thoracic medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite their growing popularity, the potential respiratory toxicity of electronic cigarettes (e-cigarettes) remains largely unknown. One potential aspect of e-cigarette toxicity is the effect of e-cigarette vapor on lung surfactant function. Lung surfactant is a mixture of lipids and proteins that lines the alveolar region. The surfactant layer reduces the surface tension of the alveolar fluid, thereby playing a crucial role in lung stability. Due to their small size, particulates in e-cigarette vapor can penetrate the deep lungs and come into contact with the lung surfactant. The current study sought to examine the potential adverse effects of e-cigarette vapor and conventional cigarette smoke on lung surfactant interfacial properties.
methodsInfasurf
resultsE-cigarette vapor regardless of the dose and flavoring of the e-liquid did not affect surfactant interfacial properties. In contrast, smoke from conventional cigarettes had a drastic, dose-dependent effect on Infasurf
conclusionsWhile both e-cigarette vapor and conventional cigarette smoke affect surfactant lateral structure, only cigarette smoke disrupts surfactant interfacial properties. The surfactant inhibitory compound in conventional cigarettes is tar, which is a product of burning and is thus absent in e-cigarette vapor.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.