Evidence map›Paper›PMID 29149503›Full record

ArticleCancer2018

Sexual functioning among young adult cancer patients: A 2-year longitudinal study.

Chiara Acquati, Brad J Zebrack, Anna C Faul, Leanne Embry, Christine Aguilar, Rebecca Block, Brandon Hayes-Lattin, David R Freyer, Steve Cole

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07658937 (Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07658937 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing

TypeinterventionalSponsorConnecticut Children's Medical CenterRan2026 to 2029Enrolled30ConditionsHealth-Related Quality-of-Life, Cancer, Health CommunicationArmsReSPECT
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

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  7. Appraisal of sexual functioning before and after cancer: insights from adolescent and young adult (AYA) cancer survivors and matched healthy controls.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Chiara AcquatiGraduate College of Social Work, University of Houston, Houston, Texas.ORCID 0000-0002-6232-5834
Brad J ZebrackSchool of Social Work, University of Michigan, Ann Arbor, Michigan.
Anna C FaulKent School of Social Work, University of Louisville, Louisville, Kentucky.
Leanne EmbryThe University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Christine AguilarThe University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Rebecca BlockMNR Analytics, Portland, Oregon.
Brandon Hayes-LattinOregon Health and Science University, Portland, Oregon.
David R FreyerChildren's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.
Steve ColeDivision of Hematology-Oncology, Department of Medicine, School of Medicine, University of California Los Angeles, Los Angeles, California.
The University of Texas Health Science Center at San Antonio · USOregon Health & Science University · USSystems Analytics (United States) · USUniversity of California, Los Angeles · USUniversity of Houston · USUniversity of Louisville · USUniversity of Michigan · USUniversity of Southern California · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
NCI NIH HHS P30 CA014089
6 · The paper itself

Abstract

backgroundCancer-related sexual dysfunction has been reported among adolescents and young adults (AYAs); however, its prevalence over time has not been examined. This longitudinal study investigated sexual dysfunction in AYAs over the course of 2 years after the initial diagnosis.

methodsYoung adult patients (18-39 years old) completed the Medical Outcomes Study Sexual Functioning Scale within the first 4 months of their diagnosis (n = 123) and again 6 (n = 107) and 24 months later (n = 95). An ordered multinomial response model analyzed changes in the probability of reporting sexual dysfunction over time and the independent effects of demographic, clinical, and psychosocial variables.

resultsMore than half of the participants reported sexual functioning to be problematic at each assessment. The probability of reporting sexual dysfunction increased over time (P < .01) and was greater for cancer patients who were female (P < .001), older (P < .01), married or in a committed relationship (P < .001), treated with chemotherapy (P < .05), and reporting comorbid psychological distress (P < .001) and lower social support (P < .05). For women, being in a relationship increased the likelihood of reporting sexual problems over time; for men, the likelihood of reporting sexual problems increased regardless of their relationship status.

conclusionsA substantial proportion of young adults report ongoing problems with sexual functioning in the first 2 years after their cancer diagnosis. These findings justify the need to evaluate and monitor sexual functioning throughout a continuum of care. Cancer 2018;124:398-405. © 2017 American Cancer Society.

Indexed as

AdolescentAdultFemaleHumansLongitudinal StudiesMaleNeoplasmsProbabilitySexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalYoung Adultadolescentsadolescents and young adults (AYAs)cancersexual functioningyoung adults

Identifiers

PMID29149503
PMCPMC7514897
OpenAlexW2769052467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.