ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017
Challenges and opportunities for pediatric severe TBI-review of the evidence and exploring a way forward.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04077411 (Approaches and Decisions for Acute Pediatric TBI), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Approaches and Decisions for Acute Pediatric TBI (ADAPT) Trial
Who cites it
15 citing papers in PubMed.
- Brain Magnetic Resonance Imaging Volumetric Measures of Functional Outcome after Severe Traumatic Brain Injury in Adolescents.Journal of neurotrauma · 2021Trial
- An update on pediatric traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Predictors of Outcome in Management of Paediatric Head Trauma in a Tertiary Healthcare Institution in North-Central Nigeria.Journal of Korean Neurosurgical Society · 2023Article
- Invasive Neuromonitoring Modalities in the Pediatric Population.Neurocritical care · 2023Review
- Magnetic Resonance Imaging Findings in Infants with Severe Traumatic Brain Injury and Associations with Abusive Head Trauma.Children (Basel, Switzerland) · 2022Article
- Continuous Electroencephalogram and Antiseizure Medication Use in an International Pediatric Traumatic Brain Injury Population.Neurocritical care · 2022Article
- Management of Severe Traumatic Brain Injury in Pediatric Patients.Frontiers in toxicology · 2022Review
- Multifaceted Benefit of Whole Blood Versus Lactated Ringer's Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice.Neurocritical care · 2021Article
- Trajectory of Long-Term Outcome in Severe Pediatric Diffuse Axonal Injury: An Exploratory Study.Frontiers in neurology · 2021Article
- A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team.Brain sciences · 2020Article
- Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies.Journal of neurotrauma · 2020Observational
- The Evolution of the Role of External Ventricular Drainage in Traumatic Brain Injury.Journal of clinical medicine · 2019Review
- Treatment of severe traumatic brain injury in German pediatric intensive care units-a survey of current practice.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Monitoring and Measurement of Intracranial Pressure in Pediatric Head Trauma.Frontiers in neurology · 2019Review
- Approaches to Multimodality Monitoring in Pediatric Traumatic Brain Injury.Frontiers in neurology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Traumatic brain injury (TBI) is a leading killer of children in the developed and developing world. Despite evidence-based guidelines and several recent clinical trials, the progress in developing best practices for children with severe TBI has been slow. This article describes (i) the burden of the disease, (ii) the inadequacies of the evidence-based guidelines, (iii) the failure of the largest clinical trials to prove their primary hypotheses, and (iv) possible advances from an observational cohort study called the Approaches and Decisions for Acute Pediatric TBI (ADAPT) Trial that has recently completed enrollment.
Indexed as
Identifiers
29149394What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.