Evidence map›Paper›PMID 29149384›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2017

Brain metabolism and severe pediatric traumatic brain injury.

Heidi Griffiths, Manu S Goyal, Jose A Pineda

Abstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Heidi GriffithsDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Manu S GoyalDepartment of Neuroradiology, Washington University School of Medicine, St. Louis, MO, USA.
Jose A PinedaDepartment of Pediatrics and Neurology, Washington University School of Medicine, St. Louis, MO, USA. pineda_j@wustl.edu.
Washington University in St. Louis · US

Funding

Saint Louis Children's Hospital Foundation PR-2016-190
6 · The paper itself

Abstract

Age-dependent changes in brain metabolism may influence the response to and tolerance of secondary insults, potentially affecting outcomes. More complete characterization of brain metabolism across the clinical trajectory of severe pediatric TBI is needed to improve our ability to measure and better mitigate the impact of secondary insults. Better management of secondary insults will impact clinical care and the probability of success of future neuroprotective clinical trials. Improved bedside monitoring and imaging technologies will be required to achieve these goals. Effective and sustained integration of brain metabolism information into the pediatric critical care setting will be equally challenging and important.

Indexed as

PediatricsBrainBrain Injuries, TraumaticChildChild, PreschoolCritical CareHumansInfantBrain metabolismSecondary injuryTraumatic brain injury

Identifiers

PMID29149384
OpenAlexW2751209941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.