ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2018
Genomic and epigenomic immunity in common bean: the unusual features of NB-LRR gene family.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Regional heritability mapping reveals genomic regions and candidate defense genes for multi-race anthracnose resistance in Phaseolus vulgaris.Scientific reports · 2026Article
- Exploiting plant immune "switches" for resistance engineering.Stress biology · 2026Review
- A panomics-driven framework for the improvement of major food legume crops: advances, challenges, and future prospects.Horticulture research · 2025Article
- Fine mapping of a new common bean anthracnose resistance gene (Co-18) to the proximal end of Pv10 in Indian landrace KRC-5.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- The pivotal ripening gene SlDML2 participates in regulating disease resistance in tomato.Plant biotechnology journal · 2023Article
- A Conserved, Serine-Rich Protein Plays Opposite Roles in N-Mediated Immunity against TMV and N-Triggered Cell Death.Viruses · 2022Article
- Genome-Wide Transcriptomic Analysis of the Effects of Infection with the Hemibiotrophic FungusPlants (Basel, Switzerland) · 2022Article
- Phaseolus vulgaris-Colletotrichum lindemuthianum Pathosystem in the Post-Genomic Era: An Update.Current microbiology · 2022Review
- Genome-wide identification and characterization of NBS-encoding genes in the sweet potato wild ancestorOpen life sciences · 2022Article
- Whole-Genome DNA Methylation Analysis inFrontiers in plant science · 2022Article
- Article
- Multifaceted Chromatin Structure and Transcription Changes in Plant Stress Response.International journal of molecular sciences · 2021Review
- Comprehensive genomic resources related to domestication and crop improvement traits in Lima bean.Nature communications · 2021Article
- Convergent Epigenetic Mechanisms Avoid Constitutive Expression of Immune Receptor Gene Subsets.Frontiers in plant science · 2021Article
- Common bean resistance to Xanthomonas is associated with upregulation of the salicylic acid pathway and downregulation of photosynthesis.BMC genomics · 2020Article
- Editorial: Evolution and Functional Mechanisms of Plant Disease Resistance.Frontiers in genetics · 2020Article
- North-Western Himalayan Common Beans: Population Structure and Mapping of Quantitative Anthracnose Resistance Through Genome Wide Association Study.Frontiers in plant science · 2020Article
- Impact of DNA Demethylases on the DNA Methylation and Transcription ofFrontiers in genetics · 2020Article
- An evolutionarily conserved non-synonymous SNP in a leucine-rich repeat domain determines anthracnose resistance in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- BABA-Induced DNA Methylome Adjustment to Intergenerational Defense Priming in Potato toFrontiers in plant science · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, a key class of genes comprising most of disease resistance (R) genes encodes Nucleotide-binding leucine-rich repeat (NL) proteins. Access to common bean (Phaseolus vulgaris) genome sequence provides unparalleled insight into the organization and evolution of this large gene family (∼400 NL) in this important crop. As observed in other plant species, most common bean NL are organized in cluster of genes. However, a particularity of common bean is that these clusters are often located in subtelomeric regions close to terminal knobs containing the satellite DNA khipu. Phylogenetically related NL are spread between different chromosome ends, suggesting frequent exchanges between non-homologous chromosomes. NL peculiar location, in proximity to heterochromatic regions, led us to study their DNA methylation status using a whole-genome cytosine methylation map. In common bean, NL genes displayed an unusual body methylation pattern since half of them are methylated in the three contexts, reminiscent of the DNA methylation pattern of repeated sequences. Moreover, 90 NL were also abundantly targeted by 24 nt siRNA, with 90% corresponding to methylated NL genes. This suggests the existence of a transcriptional gene silencing mechanism of NL through the RdDM (RNA-directed DNA methylation) pathway in common bean that has not been described in other plant species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.