ArticlePLoS neglected tropical diseases2017
The introduction of dengue follows transportation infrastructure changes in the state of Acre, Brazil: A network-based analysis.
Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- HLA alleles and dengue susceptibility across populations in the era of climate change: a comprehensive review.Frontiers in immunology · 2025Pooled it
- Characterizing dengue transmission in rural areas: A systematic review.PLoS neglected tropical diseases · 2023Pooled it
- Beyond the metropolises: the decentralization of chikungunya to non-metropolitan areas across Brazil.Cadernos de saude publica · 2026Article
- Systematic survey and spatial mapping of discarded tyres as breeding habitats ofCurrent research in parasitology & vector-borne diseases · 2026Article
- Highway paving increased dengue transmission in the Peruvian Amazon.medRxiv : the preprint server for health sciences · 2025Article
- Introduction, establishment, and distribution ofLancet regional health. Americas · 2025Article
- Review
- Spatiotemporal dataset of dengue influencing factors in Brazil based on geospatial big data cloud computing.Scientific data · 2025Article
- A nationwide joint spatial modelling of simultaneous epidemics of dengue, chikungunya, and Zika in Colombia.BMC infectious diseases · 2025Article
- Human migrations, anthropogenic changes, and insect-borne diseases in Latin America.Parasites & vectors · 2025Review
- SARS-CoV-2 Detection and Persistence in a Remote Amazonian Settlement.Journal of tropical medicine · 2025Article
- Modeling the Regional Distribution of International Travelers in Spain to Estimate Imported Cases of Dengue and Malaria: Statistical Inference and Validation Study.JMIR public health and surveillance · 2024Article
- Climate change, thermal anomalies, and the recent progression of dengue in Brazil.Scientific reports · 2024Article
- Increasing transmission of dengue virus across ecologically diverse regions of Ecuador and associated risk factors.PLoS neglected tropical diseases · 2024Article
- Phylogenetic Analysis of Transmission Dynamics of Dengue in Large and Small Population Centers, Northern Ecuador.Emerging infectious diseases · 2023Review
- Trajetorias: a dataset of environmental, epidemiological, and economic indicators for the Brazilian Amazon.Scientific data · 2023Article
- A Bayesian modelling framework to quantify multiple sources of spatial variation for disease mapping.Journal of the Royal Society, Interface · 2022Article
- Fast expansion of dengue in Brazil.Lancet regional health. Americas · 2022Article
- Receptivity to malaria: meaning and measurement.Malaria journal · 2022Review
- Silent circulation of Chikungunya virus among pregnant women and newborns in the Western Brazilian Amazon before the first outbreak of chikungunya fever.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Human mobility, presence and passive transportation of Aedes aegypti mosquito, and environmental characteristics are a group of factors which contribute to the success of dengue spread and establishment. To understand this process, we assess data from dengue national and municipal basins regarding population and demographics, transportation network, human mobility, and Ae. aegypti monitoring for the Brazilian state of Acre since the first recorded dengue case in the year 2000 to the year 2015. During this period, several changes in Acre's transport infrastructure and urbanization have been started. To reconstruct the process of dengue introduction in Acre, we propose an analytic framework based on concepts used in malaria literature, namely vulnerability and receptivity, to inform risk assessments in dengue-free regions as well as network theory concepts for disease invasion and propagation. We calculate the probability of dengue importation to Acre from other Brazilian states, the evolution of dengue spread between Acrean municipalities and dengue establishment in the state. Our findings suggest that the landscape changes associated with human mobility have created favorable conditions for the establishment of dengue virus transmission in Acre. The revitalization of its major roads, as well as the increased accessibility by air to and within the state, have increased dengue vulnerability. Unplanned urbanization and population growth, as observed in Acre during the period of study, contribute to ideal conditions for Ae. aegypti mosquito establishment, increase the difficulty in mosquito control and consequently its local receptivity.
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