Evidence map›Paper›PMID 29149072›Full record

ArticleMolecules (Basel, Switzerland)2017

Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay.

Stefanie Quosdorf, Anja Schuetz, Herbert Kolodziej

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Anti-Infective Screening of Selected Nine Cannabinoids AgainstCurrent issues in molecular biology · 2025
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  6. EPsInternational journal of molecular sciences · 2023
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  7. Review
  8. Ebola Entry Inhibitors Discovered fromInternational journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Frontiers in bioengineering and biotechnology · 2021
    Article
  13. Antiviral and Immunomodulatory Effects ofFrontiers in pharmacology · 2021
    Article
  14. Article
  15. Article
  16. Antiviral Mechanism of Action of Epigallocatechin-3-Molecules (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stefanie QuosdorfInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. stquosdorf@gmail.com.
Anja SchuetzMax-Delbrück-Centrum for Molecular Medicine, Helmholtz Protein Sample Production Facility, Robert-Rössle-Str. 10, 13125 Berlin, Germany. anja.schuetz@mdc-berlin.de.
Herbert KolodziejInstitute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2+4, 14195 Berlin, Germany. kolpharm@zedat.fu-berlin.de.
Freie Universität Berlin · DEMax Delbrück Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuraminidaseis a key enzyme in the life cycle of influenza viruses and is present in some bacterial pathogens. We here assess the inhibitory potency of plant tannins versus clinically used inhibitors on both a viral and a bacterial model neuraminidase by applying the 2'-(4-methylumbelliferyl)-α-d-

Indexed as

Enzyme AssaysAnti-Bacterial AgentsAntiviral AgentsDrug SynergismHydrolyzable TanninsInhibitory Concentration 50NeuraminidaseOseltamivirTanninsVibrio choleraeViral ProteinsZanamivirAnti-Bacterial AgentsAntiviral AgentsellagitanninHydrolyzable TanninsNA protein, influenza A virusNeuraminidaseOseltamiviroseltamivir carboxylateTanninsViral ProteinsZanamivircrystal structureinhibitionmolecular interactionsneuraminidaseoseltamivir carboxylatetanninszanamivir

Identifiers

PMID29149072
PMCPMC6150325
OpenAlexW2768371966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.