Evidence map›Paper›PMID 29148754›Full record

ArticleJournal of natural products2017

Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level.

Clemens Malainer, Daniel Schachner, Enrico Sangiovanni, Atanas G Atanasov, Stefan Schwaiger, Hermann Stuppner, Elke H Heiss, Verena M Dirsch

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Antiplasmodial Compounds fromInternational journal of molecular sciences · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Clemens MalainerDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.
Daniel SchachnerDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.
Enrico SangiovanniDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.
Atanas G AtanasovDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.ORCID 0000-0003-2545-0967
Stefan SchwaigerInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck, University Innsbruck , Innrain 80/82, Innsbruck 6020, Austria.
Hermann StuppnerInstitute of Pharmacy/Pharmacognosy, Center for Molecular Biosciences Innsbruck, University Innsbruck , Innrain 80/82, Innsbruck 6020, Austria.
Elke H HeissDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.
Verena M DirschDepartment of Pharmacognosy, University of Vienna , Althanstrasse 14, 1090 Vienna, Austria.ORCID 0000-0002-9261-5293
University of Vienna · ATUniversität Innsbruck · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The C-19 quassinoid eurycomalactone (1) has recently been shown to be a potent (IC

Indexed as

Cell AdhesionCell Adhesion MoleculesCell LineCyclin D1Endothelial CellsE-SelectinEurycomaHumansHuman Umbilical Vein Endothelial CellsNF-kappa BNF-KappaB Inhibitor alphaPhosphorylationPlant ExtractsQuassinsRNA, MessengerRNA Processing, Post-TranscriptionalCell Adhesion MoleculesCyclin D1E-SelectinNF-kappa BNF-KappaB Inhibitor alphaPlant ExtractsQuassinsRNA, MessengerTranscription Factor RelATumor Necrosis Factor-alpha

Identifiers

PMID29148754
PMCPMC5744186
OpenAlexW2770212778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.