Evidence map›Paper›PMID 29148740›Full record

ArticleBiochemistry2017

Effect of an Imposed Contact on Secondary Structure in the Denatured State of Yeast Iso-1-cytochrome c.

Travis A Danielson, Jessica M Stine, Tanveer A Dar, Klara Briknarova, Bruce E Bowler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Travis A DanielsonDepartment of Chemistry and Biochemistry, University of Montana , Missoula, Montana 59812, United States.
Jessica M StineDepartment of Chemistry and Biochemistry, University of Montana , Missoula, Montana 59812, United States.
Tanveer A DarDepartment of Chemistry and Biochemistry, University of Montana , Missoula, Montana 59812, United States.
Klara BriknarovaDepartment of Chemistry and Biochemistry, University of Montana , Missoula, Montana 59812, United States.ORCID 0000-0003-3737-9803
Bruce E BowlerDepartment of Chemistry and Biochemistry, University of Montana , Missoula, Montana 59812, United States.ORCID 0000-0003-1543-2466
University of Montana · US

Funding

Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP20GM103546 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2012 to 2021
$19.2M
Conformational Properties of Protein Denatured StatesR01GM074750 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2005 to 2009
$947k
NIGMS NIH HHS P20 GM103546NIGMS NIH HHS R01 GM074750
6 · The paper itself

Abstract

There is considerable evidence that long-range interactions stabilize residual protein structure under denaturing conditions. However, evaluation of the effect of a specific contact on structure in the denatured state has been difficult. Iso-1-cytochrome c variants with a Lys54 → His mutation form a particularly stable His-heme loop in the denatured state, suggestive of loop-induced residual structure. We have used multidimensional nuclear magnetic resonance methods to assign

Indexed as

Protein FoldingCytochromes cGuanidineHistidineLysineMutationNuclear Magnetic Resonance, BiomolecularProtein DenaturationProtein Structure, SecondarySaccharomyces cerevisiae ProteinsThermodynamicsCYC1 protein, S cerevisiaeCytochromes cGuanidineHistidineLysineSaccharomyces cerevisiae Proteins

Identifiers

PMID29148740
PMCPMC5751441
OpenAlexW2768266223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.