Evidence map›Paper›PMID 29148529›Full record

ArticleEye (London, England)2018

Anterior segment ischemia: etiology, assessment, and management.

S L Pineles, M Y Chang, E L Oltra, M S Pihlblad, J P Davila-Gonzalez, T C Sauer, F G Velez

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Changes in iris microvasculature after horizontal strabismus surgery: anterior segment OCTA combined with synoptophore-based functional assessment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Review
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  7. The temporal dynamic of bradykinin type 2 receptor effects reveals its neuroprotective role in the chronic phase of cerebral and retinal ischemic injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. A case of bilateral horizontal gaze palsy and concurrent esotropia.American journal of ophthalmology case reports · 2023
    Article
  12. Article
  13. Article
  14. Anterior segment ischemia following strabismus surgery in a young adult using gender-affirming estrogen hormone therapy.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2023
    Article
  15. Observational
  16. Article
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  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

S L PinelesStein Eye Institute, University of California, Los Angeles, Los Angeles, CA, USA.
M Y ChangUniversity of California, Davis, Sacramento, CA, USA.
E L OltraWeill Cornell Medical College, New York, NY, USA.
M S PihlbladChildren's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
J P Davila-GonzalezStein Eye Institute, University of California, Los Angeles, Los Angeles, CA, USA.
T C SauerOphthalmic Consultants of Boston-Tufts New England Eye Center, Boston, MA, USA.
F G VelezStein Eye Institute, University of California, Los Angeles, Los Angeles, CA, USA.
University of California, Los Angeles · USChildren's Hospital of Pittsburgh · USCornell University · USOlive View-UCLA Medical Center · USOphthalmic Consultants of Boston · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anterior segment ischemia (ASI) is a potentially serious but rare complication of strabismus surgery. Among several risk factors, ASI occurs after strabismus surgery because of the nature of the anterior segment circulation. Disinsertion of rectus muscles leads to a decrease in the blood supply to the various anterior segment structures. We report a series of retrospective and prospective studies performed by our group focused on determining the risk of anterior segment ischemia following strabismus surgery, diagnosis, and modifications to surgical techniques to minimize the impact on anterior segment circulation. We found a significant decrease in postoperative anterior segment blood flow when operating vertical rectus muscles. Plication procedures preserve anterior segment circulation, and modifications to the technique allow the performance of adjustable sutures. Small adjustable selective procedures that spare the ciliary vessels have been demonstrated to be effective in patients with vertical and torsional diplopia. Ciliary sparing augmented adjustable transposition surgery decreases the risk of anterior segment ischemia while allowing management of potential post-operative alignment complications. Finally, ocular coherence tomography angiography is a valuable quantitative and qualitative technique to evaluate anterior segment ischemia. Strabismus surgeons should be aware of the risks of anterior segment ischemia when operating vertical rectus muscles. Modifications to standard surgical techniques allow surgeons to perform complex strabismus surgery in patients at risk for anterior segment ischemia.

Indexed as

Eye DiseasesIschemiaOphthalmologic Surgical ProceduresAnterior Eye SegmentHumansOculomotor MusclesPostoperative ComplicationsProspective StudiesRetrospective StudiesStrabismus

Identifiers

PMID29148529
PMCPMC5811735
OpenAlexW2769959199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.