Evidence map›Paper›PMID 29148090›Full record

ArticleAmerican journal of industrial medicine2018

Assessment of cumulative health risk in the World Trade Center general responder cohort.

Ghalib A Bello, Susan L Teitelbaum, Roberto G Lucchini, Christopher R Dasaro, Moshe Shapiro, Julia R Kaplan, Michael A Crane, Denise J Harrison, Benjamin J Luft, Jacqueline M Moline and 2 more

Abstract read
In one paragraph

Article in American journal of industrial medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Asthma-COPD overlap in World Trade Center Health Registry enrollees, 2015-2016.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ghalib A BelloDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID http://orcid.org/0000-0002-7893-743X
Susan L TeitelbaumDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Roberto G LucchiniDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID http://orcid.org/0000-0002-9723-0237
Christopher R DasaroDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Moshe ShapiroDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Julia R KaplanDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Michael A CraneDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Denise J HarrisonDepartment of Environmental Medicine, Bellevue Hospital Center/New York University School of Medicine, New York, New York.
Benjamin J LuftDepartment of Medicine, Stony Brook University Medical Center, Stony Brook, New York.
Jacqueline M MolineDepartment of Occupational Medicine, Epidemiology and Prevention, Hofstra Northwell School of Medicine at Hofstra University, Hempstead, New York.
Iris G UdasinEnvironmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical Center, Piscataway, New Jersey.
Andrew C ToddDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.

Funding

CDC HHS HHSD200201139361CCDC HHS HHSD200201139384CCDC HHS HHSD200201139385CCDC HHS HHSD200201139388CNIOSH CDC HHS HHSD200200200384CNIOSH CDC HHS HHSD200201139356CNIOSH CDC HHS HHSD200201139377CNIOSH CDC HHS U10 OH008216NIOSH CDC HHS U10 OH008223NIOSH CDC HHS U10 OH008225NIOSH CDC HHS U10 OH008232NIOSH CDC HHS U10 OH008239NIOSH CDC HHS U10 OH008275
6 · The paper itself

Abstract

backgroundMultiple comorbidities have been reported among rescue/recovery workers responding to the 9/11/2001 WTC disaster. In this study, we developed an index that quantifies the cumulative physiological burden of comorbidities and predicts life expectancy in this cohort.

methodsA machine learning approach (gradient boosting) was used to model the relationship between mortality and several clinical parameters (laboratory test results, blood pressure, pulmonary function measures). This model was used to construct a risk index, which was validated by assessing its association with a number of health outcomes within the WTC general responder cohort.

resultsThe risk index showed significant associations with mortality, self-assessed physical health, and onset of multiple chronic conditions, particularly COPD, hypertension, asthma, and sleep apnea.

conclusionAs an aggregate of several clinical parameters, this index serves as a cumulative measure of physiological dysregulation and could be utilized as a prognostic indicator of life expectancy and morbidity risk.

Indexed as

AdultCohort StudiesEmergency RespondersFemaleHumansMaleMiddle AgedOccupational DiseasesOccupational ExposureRescue WorkRisk AssessmentSeptember 11 Terrorist AttacksYoung Adult9/11Health Risk Indexmortalityphysiological dysregulationWorld Trade Center

Identifiers

PMID29148090
PMCPMC12798799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.