ArticleEnvironmental science and pollution research international2018
Low atrazine dosages reduce sperm quality of Calomys laucha mice.
Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Meta-analysis and experimental validation identified atrazine as a toxicant in the male reproductive system.Environmental science and pollution research international · 2021Pooled it
- An integrated experimental and computational systems biology analysis reveals molecular mechanisms underlying reproductive toxicity induced by manganese and atrazine.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Dietary exposure to pesticides in poultry: From semen quality to embryonic mortality and tissue accumulation.Poultry science · 2026Article
- An In Vivo and In Silico Experimental Approach on Rats' Neurobehaviour upon Treatment with Atrazine and Manganese.Molecular neurobiology · 2025Article
- Manganese mitigates atrazine-induced oxidative stress and hepatorenal toxicity: insights from network pharmacology and in vivo experimentation.BMC pharmacology & toxicology · 2025Article
- Review
- Atrazine: cytotoxicity, oxidative stress, apoptosis, testicular effects and chemopreventive Interventions.Frontiers in toxicology · 2023Review
- Chronic ciprofloxacin and atrazine co-exposure aggravates locomotor and exploratory deficits in non-target detritivore speckled cockroach (Nauphoeta cinerea).Environmental science and pollution research international · 2021Article
- Multimarker approach to assess the exposure of the wild rodent Calomys laucha to a simulated crude oil spill.Environmental science and pollution research international · 2021Article
- Atrazine exposure in gestation and breastfeeding affects Calomys laucha sperm cells.Environmental science and pollution research international · 2019Article
- Effects of Bisphenol A on redox balance in red blood and sperm cells and spermatic quality in zebrafish Danio rerio.Ecotoxicology (London, England) · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproductive effects caused by the exposure to environmentally relevant dosages of atrazine on wild animals are poorly understood. This study evaluated the effects of three dosages of atrazine on sperm parameters of adult Calomys laucha males. Adult mice were orally exposed to dosages of 0 (water and vehicle control), 0.1, 1, and 10 mg/kg of animal weight for a 21-day period. Following exposure, analyses were performed to determine sperm motility parameters, plasma membrane integrity and fluidity, mitochondrial functionality, acrosome integrity, DNA damage, lipid peroxidation, and production of reactive oxygen species (ROS) in the sperm samples. Total and progressive motility were reduced in all dosages in comparison to control groups. Membrane integrity and mitochondrial functionality of sperm were reduced in all dosages, and the sperm membrane fluidity increased in the higher dosages of atrazine (1 and 10 mg/kg), in comparison with the vehicle control. A decrease in the acrosome integrity was noted at 10 mg/kg of atrazine, compared to the control groups. The integrity of DNA, ROS generation, and lipid peroxidation of sperm showed no significant differences when compared with the control groups. These results suggest that exposure to low dosages of atrazine can affect sperm parameters of Calomys laucha and therefore reduce the reproductive capacity of wild rodent species.
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Registered trials
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