Evidence map›Paper›PMID 29147884›Full record

ArticleJournal of neurovirology2017

Ocular flutter following Zika virus infection.

Emely Karam, Jose Giraldo, Flor Rodriguez, Carlos E Hernandez-Pereira, Alfonso J Rodriguez-Morales, Gabriela M Blohm, Alberto E Paniz-Mondolfi

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  3. Non-nystagmus hyperkinetic eye movement disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Emely KaramDepartment of Ophtalmology, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Jose GiraldoDepartment of Ophtalmology, Hospital Internacional Barquisimeto, Barquisimeto, Lara, Venezuela.
Flor RodriguezDepartment of Ophtalmology, Grupo Médico La Sagrada Familia, Lechería, Anzoategui, Venezuela.
Carlos E Hernandez-PereiraInfectious Diseases Research Incubator and the Zoonosis and Emerging Pathogens Regional Collaborative Network, Barquisimeto, Lara, Venezuela.
Alfonso J Rodriguez-MoralesColombian Collaborative Network on Zika (RECOLZIKA), Pereira, Risaralda, Colombia.
Gabriela M BlohmDepartment of Biology, College of Liberal Arts and Sciences, University of Florida, Gainesville, FL, USA.
Alberto E Paniz-MondolfiDepartment of Infectious Diseases and Tropical Medicine, Hospital Internacional Barquisimeto, Barquisimeto, Lara, Venezuela. alberto.paniz-mondolfi@yale.edu.
Centro Médico Docente La Trinidad · VETechnological University of Pereira · COUniversidad Centroccidental Lisandro Alvarado · VEUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) is an emerging flavivirus which has been linked to a number of neurologic manifestations such as Guillain-Barré syndrome (GBS), transverse myelitis, and meningo-encephalitis. Ophthalmologic manifestations are increasingly being reported; however, ocular dyskinesias have not been described in this context to date. Herein, we report a case of a 22-year-old female who presented with ocular flutter and associated Guillain-Barré syndrome following acute ZIKV infection. We speculate that although such symptoms may have originated from a direct viral insult, a post-infectious autoimmune mechanism may not be excluded. Physicians should include ZIKV as well as other flaviviruses in their diagnostic workup for all patients with ocular flutter/opsoclonus, after excluding other non-infectious causes of central nervous system pathology. To the best of our knowledge, this is the first report on the association of ocular flutter, GBS, and ZIKV infection.

Indexed as

AcyclovirAntibodies, ViralAntiviral AgentsAtaxiaFemaleGuillain-Barre SyndromeHumansImmunoglobulins, IntravenousOcular Motility DisordersYoung AdultZika VirusZika Virus InfectionAcyclovirAntibodies, ViralAntiviral AgentsImmunoglobulins, IntravenousGuillain-Barré syndromeOcular flutterViralZika virus

Identifiers

PMID29147884
OpenAlexW2769217408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.