Evidence map›Paper›PMID 29147866›Full record

ReviewMycopathologia2018

A Review of Onychomycosis Due to Aspergillus Species.

Felix Bongomin, C R Batac, Malcolm D Richardson, David W Denning

Open access · hybridAbstract readReview
In one paragraph

Review in Mycopathologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 100 citations in OpenAlex.

  1. Review
  2. Article
  3. Antifungal Mechanism Effect of Artemisinin onPharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Broad-Spectrum Antimicrobial Potential of the γ-Core Motif Peptides ofInternational journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Emergence ofMini reviews in medicinal chemistry · 2024
    Review
  12. Review
  13. Pathogens (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Studies in mycology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Felix BongominThe National Aspergillosis Centre, Education and Research Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester, M23 9LT, UK.
C R BatacSkin Study Group, Institute of Herbal Medicine, National Institutes of Health, University of the Philippines - Manila, Manila, Philippines.
Malcolm D RichardsonThe National Aspergillosis Centre, Education and Research Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester, M23 9LT, UK.
David W DenningThe National Aspergillosis Centre, Education and Research Centre, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Southmoor Road, Manchester, M23 9LT, UK. ddenning@manchester.ac.uk.ORCID http://orcid.org/0000-0001-5626-2251
Manchester Academic Health Science Centre · GBManchester University NHS Foundation Trust · GBUniversity of Manchester · GBUniversity of the Philippines Manila · PH

Funding

Global Action Fund for Fungal Infections N/A
6 · The paper itself

Abstract

Aspergillus spp. are emerging causative agents of non-dermatophyte mould onychomycosis (NDMO). New Aspergillus spp. have recently been described to cause nail infections. The following criteria are required to diagnose onychomycosis due to Aspergillus spp.: (1) positive direct microscopy and (2) repeated culture or molecular detection of Aspergillus spp., provided no dermatophyte was isolated. A review of 42 epidemiological studies showed that onychomycosis due to Aspergillus spp. varies between < 1 and 35% of all cases of onychomycosis in the general population and higher among diabetic populations accounting for up to 71% and the elderly; it is very uncommon among children and adolescence. Aspergillus spp. constitutes 7.7-100% of the proportion of NDMO. The toenails are involved 25 times more frequently than fingernails. A. flavus, A. terreus and A. niger are the most common aetiologic species; other rare and emerging species described include A. tubingensis, A. sydowii, A. alliaceus, A. candidus, A. versicolor, A. unguis, A. persii, A. sclerotiorum, A. uvarum, A. melleus, A. tamarii and A. nomius. The clinical presentation of onychomycosis due to Aspergillus spp. is non-specific but commonly distal-lateral pattern of onychomycosis. A negative culture with a positive KOH may point to a NDM including Aspergillus spp., as the causative agent of onychomycosis. Treatment consists of systemic therapy with terbinafine or itraconazole.

Indexed as

AspergillosisAspergillusCommunicable Diseases, EmergingHumansMicrobiological TechniquesMicroscopyOnychomycosisPrevalenceRisk FactorsAspergillusClinical featuresEpidemiologyMycologyOnychomycosis

Identifiers

PMID29147866
PMCPMC5958150
OpenAlexW2770594644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.