Evidence map›Paper›PMID 29147774›Full record

ArticleLung2018

Assessment of Mediastinal Lymph Node Size in Pneumococcal Pneumonia with Bacteremia.

Amit Chopra, Aakash Modi, Haroon Chaudhry, Recai Yucel, Neha Rane, John Fantauzzi, Frederic J Hellwitz, Marc A Judson

Abstract read
PubMed Publisher
In one paragraph

Article in Lung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Amit ChopraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Albany Medical College, MC-91, 47 New Scotland Avenue, Albany, NY, 12208, USA. chopraa1@mail.amc.edu.ORCID 0000-0001-6064-0956
Aakash ModiDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Albany Medical College, MC-91, 47 New Scotland Avenue, Albany, NY, 12208, USA.
Haroon ChaudhryDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Albany Medical College, MC-91, 47 New Scotland Avenue, Albany, NY, 12208, USA.
Recai YucelDepartment of Epidemiology and Biostatistics, School of Public Health, SUNY at Albany, Rensselaer, NY, 12144, USA.
Neha RaneDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Albany Medical College, MC-91, 47 New Scotland Avenue, Albany, NY, 12208, USA.
John FantauzziDepartment of Radiology, Albany Medical Center, Albany, NY, USA.
Frederic J HellwitzDepartment of Radiology, Albany Medical Center, Albany, NY, USA.
Marc A JudsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Albany Medical College, MC-91, 47 New Scotland Avenue, Albany, NY, 12208, USA.
Albany Medical Center Hospital · USUniversity at Albany, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe significance of mediastinal lymphadenopathy in bacterial pneumonia is unclear.

methodsWe performed a retrospective analysis of mediastinal lymph node size determined by chest CT in patients with bacteremic pneumococcal pneumonia. All patients who had positive blood cultures for streptococcus pneumonia over an 11-year period and had a chest CT scan (index CT) within 2 weeks of the positive blood culture were included in the study. Two thoracic radiologists and one pulmonologist independently examined the index CT plus any chest CT scans performed prior (pre-CT) or after (post-CT) the bacteremic episode.

resultsThe study cohort of 49 patients was 57% male, 65% White, with mean age of 53 (SD = 20) years. Mediastinal lymphadenopathy was detected in 25/49 (51%) of the cases. The mean size of the largest mediastinal lymph node in short axis was 0.99 (SD = 0.71), ranging from 0.0 to 2.05 cm. There was no correlation noted between the number of lobes involved with pneumonia, and the size of the largest mediastinal lymph node (p = 0.33) or the number of pathologically enlarged mediastinal lymph nodes (p = 0.08). There was a statistically significant increase in the mean size of the largest lymph node between the pre-CT and index-CT group (p = 0.02), and decrease between the index-CT group and the post-CT (p = 0.03).

conclusionPneumococcal pneumonia with bacteremia is associated with mild mediastinal lymph node enlargement. The presence of marked mediastinal lymphadenopathy (short axis LN size > 2 cm) should not be assumed from pneumococcal pneumonia.

Indexed as

AdultAgedBacteremiaFemaleHumansLymphadenopathyLymph NodesMaleMediastinumMiddle AgedOrgan SizePneumonia, PneumococcalRetrospective StudiesTomography, X-Ray ComputedBacteremiaComputed tomographyMediastinal lymphadenopathyPneumoniaStreptococcus pneumoniae

Identifiers

PMID29147774
OpenAlexW2768270746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.