Evidence map›Paper›PMID 29147764›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2018

Prospective evaluation of

Ivan Jambor, Anna Kuisma, Esa Kähkönen, Jukka Kemppainen, Harri Merisaari, Olli Eskola, Jarmo Teuho, Ileana Montoya Perez, Marko Pesola, Hannu J Aronen and 3 more

Registry-linked trialAbstract readClinical TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03373006 (A Phase II Study to Evaluate Axumin PET/CT for Risk Stratification for Laser Focal Therapy of Intermediate Risk Localized Prostate Cancer), which is not on this map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03373006 phase2completednot on this map

A Phase II Study to Evaluate Axumin PET/CT for Risk Stratification for Laser Focal Therapy of Intermediate Risk Localized Prostate Cancer

TypeinterventionalSponsorHALO DiagnosticsRan2018 to 2020Enrolled20ConditionsProstate CancerArmsAxumin PET/CT
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Radiology. Imaging cancer · 2022
    Pooled it
  2. Pooled it
  3. The Diagnostic Role ofFrontiers in oncology · 2021
    Pooled it
  4. Pooled it
  5. [European journal of nuclear medicine and molecular imaging · 2021
    Trial
  6. Trial
  7. Clinical PET/MR.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  8. Article
  9. International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Axumin (World journal of urology · 2022
    Article
  15. Review
  16. Review
  17. Utility ofAJR. American journal of roentgenology · 2021
    Article
  18. The Role of [Cancers · 2021
    Article
  19. Novel PET imaging methods for prostate cancer.World journal of urology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ivan JamborDepartment of Diagnostic Radiology, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 52, FI-20521, Turku, Finland. ivan.jambor@utu.fi.
Anna KuismaDepartment of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland.
Esa KähkönenDepartment of Urology, Turku University Hospital, Turku, Finland.
Jukka KemppainenTurku PET Centre, Turku, Finland.
Harri MerisaariDepartment of Diagnostic Radiology, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 52, FI-20521, Turku, Finland.
Olli EskolaTurku PET Centre, Turku, Finland.
Jarmo TeuhoTurku PET Centre, Turku, Finland.
Ileana Montoya PerezDepartment of Diagnostic Radiology, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 52, FI-20521, Turku, Finland.
Marko PesolaDepartment of Diagnostic Radiology, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 52, FI-20521, Turku, Finland.
Hannu J AronenDepartment of Diagnostic Radiology, University of Turku, Kiinamyllynkatu 4-8, P.O. Box 52, FI-20521, Turku, Finland.
Peter J BoströmDepartment of Urology, Turku University Hospital, Turku, Finland.
Pekka TaimenDepartment of Pathology, University of Turku and Turku University Hospital, Turku, Finland.
Heikki MinnTurku PET Centre, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to evaluate

methodsTwenty-six men with histologically confirmed PCa underwent PET/CT immediately after injection of 369 ± 10 MBq

resultsIn the visual analysis, 164/312 (53%) regions contained PCa, and 41 tumor foci were identified. PET/CT demonstrated the highest sensitivity at 87% while its specificity was low at 56%. The AUC of both PET/MRI and mpMRI significantly (p < 0.01) outperformed that of PET/CT while no differences were detected between PET/MRI and mpMRI. SUV

conclusionsQuantitative

Indexed as

Carboxylic AcidsCyclobutanesMagnetic Resonance ImagingPositron Emission Tomography Computed TomographyAgedHumansMaleMiddle AgedNeoplasm StagingProspective StudiesProstatic NeoplasmsRiskSensitivity and SpecificityCarboxylic AcidsCyclobutanesfluciclovine F-1818F-FACBCDiffusion-weighted imagingPET/CTPET/MRIProstate cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.