ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2018
The association between childhood fractures and adolescence bone outcomes: a population-based study, the Tromsø Study, Fit Futures.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Fracture Incidence With 6-9 Years of Daily School Physical Activity: Lower Relative Fracture Risk at the End of the Intervention But Not After.Scandinavian journal of medicine & science in sports · 2026Article
- Global burden of pediatric fracture (1992-2021) and projections of future disease burden trends.BMC pediatrics · 2025Article
- Trauma Outcomes in Pediatric Nonfatal Road Traffic Accidents.Children (Basel, Switzerland) · 2024Article
- Children's outcomes in road traffic accidents: challenges for personal injury assessment.Forensic sciences research · 2023Article
- Effect of obesity status on adolescent bone mineral density and saturation effect: A cross-sectional study.Frontiers in endocrinology · 2022Article
- The Mediating Role of Lean Soft Tissue in the Relationship between Somatic Maturation and Bone Density in Adolescent Practitioners and Non-Practitioners of Sports.International journal of environmental research and public health · 2021Article
- Preschool Obesity Is Associated With an Increased Risk of Childhood Fracture: A Longitudinal Cohort Study of 466,997 Children and Up to 11 Years of Follow-up in Catalonia, Spain.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020Article
- The Utility of DXA Assessment at the Forearm, Proximal Femur, and Lateral Distal Femur, and Vertebral Fracture Assessment in the Pediatric Population: 2019 ISCD Official Position.Journal of clinical densitometry : the official journal of the International Society for Clinical DensitometryReview
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Authors and funding
10 authors at 7 institutions in 5 countries.
Funding
Abstract
Childhood fracture may predict persistent skeletal fragility, but it may also reflect high physical activity which is beneficial to bone development. We observe a difference in the relationship between previous fracture and bone outcome across physical activity level and sex. Further elaboration on this variation is needed. PURPOSE: Childhood fracture may be an early marker of skeletal fragility, or increased levels of physical activity (PA), which are beneficial for bone mineral accrual. This study investigated the association between a previous history of childhood fracture and adolescent bone mineral outcomes by various PA levels.
methodsWe recruited 469 girls and 492 boys aged 15-18 years to this study. We assessed PA levels by questionnaire and measured areal bone mineral density (aBMD) and bone mineral content (BMC) using dual-energy X-ray absorptiometry (DXA) at arm, femoral neck (FN), total hip (TH), and total body (TB) and calculated bone mineral apparent density (BMAD, g/cm
resultsGirls with and without a previous history of fracture had similar BMC, aBMD, and BMAD at all sites. In multiple regression analyses stratified by physical activity intensity (PAi), there was a significant negative association between fracture and aBMD-TH and BMC-FN yet only in girls reporting low PAi. There was a significant negative association between forearm fractures, BMAD-FN, and BMAD-arm among vigorously active boys.
conclusionOur findings indicate a negative association between childhood fractures and aBMD/BMC in adolescent girls reporting low PAi. In boys, such an association appears only in vigorously active participants with a history of forearm fractures.
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Registered trials
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