Evidence map›Paper›PMID 29147608›Full record

ReviewOncoimmunology

The prognostic role of tumor infiltrating T-lymphocytes in squamous cell carcinoma of the head and neck: A systematic review and meta-analysis.

Emma J de Ruiter, Marc L Ooft, Lot A Devriese, Stefan M Willems

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05375266 (Immune Biomarker Study for Head and Neck Cancer), which is not on this map. Cited by 213 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 14 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05375266 recruitingnot on this map

Immune Biomarker Study for Head and Neck Cancer

TypeobservationalSponsorUniversity of Erlangen-Nürnberg Medical SchoolRan2022 to 2027Enrolled1,100ConditionsHead and Neck Cancer, Oral Cavity Cancer, Oropharyngeal Cancer, Hypopharyngeal CancerArmsSampling
3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 14 syntheses or guidelines pooled it, 336 citations in OpenAlex.

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  7. Prognostic significance of tumor-infiltrating lymphocytes and macrophages in nasopharyngeal carcinoma: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Pooled it
  8. Autoimmune disease and oral squamous cell carcinoma: A systematic review.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2021
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153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Emma J de RuiterDepartment of Pathology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
Marc L OoftDepartment of Pathology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
Lot A DevrieseDepartment of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
Stefan M WillemsDepartment of Pathology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
University Medical Center Utrecht · NLHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

head and neck squamous cell carcinoma (HNSCC)prognostic biomarkerssystematic reviewT cellstumor infiltrating lymphocytes (TILs)

Identifiers

PMID29147608
PMCPMC5674970
OpenAlexW2744621424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.