Evidence map›Paper›PMID 29147604›Full record

ArticleOncoimmunology

TAP1 down-regulation elicits immune escape and poor prognosis in colorectal cancer.

Agnes Ling, Anna Löfgren-Burström, Pär Larsson, Xingru Li, Maria L Wikberg, Åke Öberg, Roger Stenling, Sofia Edin, Richard Palmqvist

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 111 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Agnes LingDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Anna Löfgren-BurströmDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Pär LarssonDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Xingru LiDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Maria L WikbergDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Åke ÖbergDepartment of Surgical and Perioperative Sciences, Surgery, Umeå University, Umeå, Sweden.
Roger StenlingDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Sofia EdinDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Richard PalmqvistDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-tumor immune response has been shown to be of great prognostic importance in colorectal cancer (CRC) and so has the tumors ability for immune evasion. Our aim of this study was to investigate tumor factors that influence immunity. We used a gene expression array to search for potential mechanisms of tumor immune escape. One candidate gene identified was

Indexed as

antigen presentationcolorectal cancerimmune escapeprognosisTAP1

Identifiers

PMID29147604
PMCPMC5674960
OpenAlexW2742515377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.