Evidence map›Paper›PMID 29147022›Full record

ArticleNature communications2017

Conventional CD4

Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, Jesús Osuna-Pérez, Mónica Torres-Torresano, Virgina Zorita, Ana Martínez-Riaño, Viola Boccasavia, Aldo Borroto, Gloria Martínez Del Hoyo, José María González-Granado and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Cytotoxic CD4Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Nanomaterials Trigger Functional Anti-Tumoral Responses in Primary Human Immune Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. A novel and efficient method to induce allospecific CD8Journal of clinical laboratory analysis · 2021
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Aránzazu Cruz-AdaliaDepartment of Molecular & Cellular Biology, Centro Nacional de Biotecnología; Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3, 28049, Madrid, Spain. acruz@cnb.csic.es.
Guillermo Ramirez-SantiagoDepartment of Molecular & Cellular Biology, Centro Nacional de Biotecnología; Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3, 28049, Madrid, Spain.
Jesús Osuna-PérezDepartment of Molecular & Cellular Biology, Centro Nacional de Biotecnología; Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3, 28049, Madrid, Spain.
Mónica Torres-TorresanoDepartment of Molecular & Cellular Biology, Centro Nacional de Biotecnología; Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3, 28049, Madrid, Spain.
Virgina ZoritaCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, 28029, Madrid, Spain.
Ana Martínez-RiañoDepartment of Cell Biology and Immunology, Centro de Biología Molecular Severo Ochoa (CBMSO); Nicolás Cabrera 1, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Viola BoccasaviaDepartment of Cell Biology and Immunology, Centro de Biología Molecular Severo Ochoa (CBMSO); Nicolás Cabrera 1, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Aldo BorrotoDepartment of Cell Biology and Immunology, Centro de Biología Molecular Severo Ochoa (CBMSO); Nicolás Cabrera 1, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Gloria Martínez Del HoyoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, 28029, Madrid, Spain.
José María González-GranadoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernández Almagro 3, 28029, Madrid, Spain.
Balbino AlarcónDepartment of Cell Biology and Immunology, Centro de Biología Molecular Severo Ochoa (CBMSO); Nicolás Cabrera 1, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Francisco Sánchez-MadridHospital de la Princesa, Instituto de Investigación Sanitaria Princesa, 28006, Madrid, Spain.
Esteban VeigaDepartment of Molecular & Cellular Biology, Centro Nacional de Biotecnología; Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3, 28049, Madrid, Spain. eveiga@cnb.csic.es.ORCID http://orcid.org/0000-0002-7333-2466
Consejo Superior de Investigaciones Científicas · ESCentro de Biología Molecular Severo Ochoa · ESSpanish National Centre for Cardiovascular Research · ESHospital Universitario de La Princesa · ES

Funding

European Research Council 294340European Research Council 334763
6 · The paper itself

Abstract

Bacterial phagocytosis and antigen cross-presentation to activate CD8

Indexed as

AnimalsAntigen PresentationAntigens, BacterialCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCells, CulturedCross-PrimingCytotoxicity, ImmunologicImmunological SynapsesImmunologic MemoryMice, Inbred C57BLMice, TransgenicPhagocytosisProgrammed Cell Death 1 ReceptorAntigens, BacterialPdcd1 protein, mouseProgrammed Cell Death 1 Receptor

Identifiers

PMID29147022
PMCPMC5691066
OpenAlexW2769782093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.