ArticleScientific reports2017
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Cost-Effective rhamnolipids production from corn Bran and their application in essential oil extraction.World journal of microbiology & biotechnology · 2026Article
- Impact of larval diet on fitness outcomes of Aedes aegypti mosquitoes infected with wAlbB and wMelM.Parasites & vectors · 2025Article
- Life table variations inFrontiers in insect science · 2025Article
- Characteristics of a Spray-Dried Porcine Blood Meal forInsects · 2024Article
- Effects of a blood-free mosquito diet on fitness and gonotrophic cycle parameters of laboratory reared Anopheles gambiae sensu stricto.Parasites & vectors · 2024Article
- Lipidomic Profiling Reveals Concerted Temporal Patterns of Functionally Related Lipids inMetabolites · 2023Article
- Ad libitum consumption of protein- or peptide-sucrose solutions stimulates egg formation by prolonging the vitellogenic phase of oogenesis in anautogenous mosquitoes.Parasites & vectors · 2022Article
- Review
- Long-Term Mosquito culture with SkitoSnack, an artificial blood meal replacement.PLoS neglected tropical diseases · 2020Article
- Detection of Yellow Fever Virus in Sylvatic Mosquitoes during Disease Outbreaks of 2017⁻2018 in Minas Gerais State, Brazil.Insects · 2019Article
- Article
- Effects of Alternative Blood Sources onInsects · 2018Article
- The Effect of SkitoSnack, an Artificial Blood Meal Replacement, on Aedes aegypti Life History Traits and Gut Microbiota.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endosymbiotic bacterium Wolbachia spreads rapidly through populations of Aedes aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue and Zika viruses. Mosquito control programs aimed at limiting transmission of these viruses are ongoing in multiple countries, yet there is a dearth of mass rearing infrastructure specific to Wolbachia-infected mosquitoes. One example is the lack of a blood meal substitute, which accounts for the Wolbachia-specific physiological changes in infected mosquitoes, that allows the bacterium to spread, and block viral infections. To that end, we have developed a blood meal substitute specifically for mosquitoes infected with the wMel Wolbachia strain. This diet, ADM, contains milk protein, and infant formula, dissolved in a mixture of bovine red blood cells and Aedes physiological saline, with ATP as a phagostimulant. Feeding with ADM leads to high levels of viable egg production, but also does not affect key Wolbachia parameters including, bacterial density, cytoplasmic incompatibility, or resistance to infection with Zika virus. ADM represents an effective substitute for human blood, which could potentially be used for the mass rearing of wMel-infected A. aegypti, and could easily be optimized in the future to improve performance.
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