Evidence map›Paper›PMID 29146867›Full record

ArticleThorax2018

High prevalence of TB disease in contacts of adults with extrapulmonary TB.

Tom Wingfield, Peter MacPherson, Paul Cleary, L Peter Ormerod

Open access · hybridAbstract readLetter
In one paragraph

Article in Thorax, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Tuberculosis prevention: current strategies and future directions.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2024
    Review
  5. Outcomes of TB contact tracing and predictors of success: a 10-year retrospective cohort analysis in Birmingham, UK.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Tom WingfieldDepartment of Clinical Infection, Microbiology, and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.ORCID 0000-0001-8433-6887
Peter MacPhersonDepartment of Public Health, Cheshire and Merseyside Health Protection Team, Public Health England North West, Liverpool, UK.
Paul ClearyDepartment of Public Health, Cheshire and Merseyside Health Protection Team, Public Health England North West, Liverpool, UK.
L Peter OrmerodLancashire Postgraduate School of Medicine, University of Central Lancashire, Preston, UK.
Liverpool School of Tropical Medicine · GBPublic Health England · GBUniversity of Lancashire · GBUniversity of Liverpool · GB

Funding

Department of HealthMedical Research Council MR/K007467/1Wellcome TrustWellcome Trust 206575/Z/17/ZWellcome Trust 209075/Z/17/Z
6 · The paper itself

Abstract

UK guidelines no longer recommend routine screening of household contacts of adult patients with extrapulmonary TB (EPTB). From 27 March 2012 to 28 June 2016, we investigated the prevalence of active TB disease in household contacts of 1023 EPTB index cases in North West England, and compared estimates with: published new entrant migrant screening programme prevalence (~147/100 000 person-years); London-based contact screening data (700/100 000 contacts screened); and National Institute for Health and Care Excellence (NICE) new entrant TB screening thresholds (TB prevalence >40/100 000 people). Active TB disease prevalence in EPTB contacts was 440/100 000 contacts screened, similar to UK new entrant screening programmes, London EPTB contact prevalence and >10 times NICE's threshold for new entrant screening. The decision to no longer recommend routine screening of EPTB contacts should be re-evaluated and cost-effectiveness analyses of screening strategies for EPTB contacts should be performed.

Indexed as

AdultContact TracingFemaleHumansLondonMalePopulation SurveillancePrevalenceRetrospective StudiesTransients and MigrantsTuberculosis, Pulmonaryclinical epidemiologytuberculosis

Identifiers

PMID29146867
PMCPMC6204960
OpenAlexW2768732241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.