ArticleBMJ open2017
Qualitative evaluation of a deferred consent process in paediatric emergency research: a PREDICT study.
Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Views on consent approaches used in emergency and critical care research: a rapid, systematic review.Trials · 2026Pooled it
- Deferred consent in emergency obstetric research: findings from qualitative interviews with women and recruiters in theBMJ open · 2022Trial
- Routine gastric residual volume measurement to guide enteral feeding in mechanically ventilated infants and children: the GASTRIC feasibility study.Health technology assessment (Winchester, England) · 2020Trial
- Attitudes and awareness in autonomous decision on medical treatment or inclusion in clinical trials amongst Slovenian adolescents: an online survey.BMC medical education · 2024Article
- Paediatric systemic inflammatory response syndrome (SIRS) and the development of patient-specific therapy: ethical perspectives through experts' opinions.Frontiers in public health · 2024Article
- Biobanking and consenting to research: a qualitative thematic analysis of young people's perspectives in the North East of England.BMC medical ethics · 2023Article
- Insisting on prospective consent in paediatric critical care research may be throwing the baby out with the bathwater.Journal of paediatrics and child health · 2022Article
- Consent models in Canadian critical care randomized controlled trials: a scoping review.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Patient and proxies' attitudes towards deferred consent in randomised trials of acute treatment for stroke: A qualitative survey.European stroke journal · 2021Article
- Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial: a mixed-methods study in India, Sri Lanka and Bangladesh.BMJ global health · 2021Article
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- A Formative Qualitative Study on the Acceptability of Deferred Consent in Adult Emergency Care Research in Malawi.Journal of empirical research on human research ethics : JERHRE · 2019Article
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- Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA challenge of conducting research in critically ill children is that the therapeutic window for the intervention may be too short to seek informed consent prior to enrolment. In specific circumstances, most international ethical guidelines allow for children to be enrolled in research with informed consent obtained later, termed deferred consent (DC) or retrospective consent. There is a paucity of data on the attitudes of parents to this method of enrolment in paediatric emergency research.
objectivesTo explore the attitudes of parents to the concept of DC and to expand the knowledge of the limitations to informed consent and DC in these situations.
methodChildren presenting with uncomplicated febrile seizures or bronchiolitis were identified from three separate hospital emergency department databases. Parents were invited to participate in a semistructured telephone interview exploring themes of limitations of prospective informed consent, acceptability of the DC process and the most appropriate time to seek DC. Transcripts underwent inductive thematic analysis with intercoder agreement, using Nvivo 11 software.
resultsA total of 39 interviews were conducted. Participants comprehended the limitations of informed consent under emergency circumstances and were generally supportive of DC. However, they frequently confused concepts of clinical care and research, and support for participation was commonly linked to their belief of personal benefit.
conclusionParticipants acknowledged the requirement for alternatives to prospective informed consent in emergency research, and were supportive of the concept of DC. Our results suggest that current research practice seems to align with community expectations.
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