Evidence map›Paper›PMID 29146532›Full record

ArticleJournal of the American College of Cardiology2018

Potential U.S. Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline.

Paul Muntner, Robert M Carey, Samuel Gidding, Daniel W Jones, Sandra J Taler, Jackson T Wright, Paul K Whelton

Abstract read
In one paragraph

Article in Journal of the American College of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Associations of Hypertension and Orthostatic Hypotension With Subclinical Cardiovascular Disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
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  13. Is it Possible to Significantly Modify Blood Pressure with a Combined Nutraceutical on Top of a Healthy Diet? The Results of a Pilot Clinical Trial.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018
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  19. Untreated Hypertension and Diabetes in the Chest Pain Observation Unit.The western journal of emergency medicine · 2025
    Observational
  20. Article

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: pmuntner@uab.edu.
Robert M CareyDepartment of Medicine, University of Virginia, Charlottesville, Virginia.
Samuel GiddingNemours Cardiac Center, A. I. DuPont Hospital for Children, Wilmington, Delaware.
Daniel W JonesDepartment of Medicine, University of Mississippi, Jackson, Mississippi.
Sandra J TalerDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Jackson T WrightDivision of Nephrology and Hypertension, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Paul K WheltonDepartment of Epidemiology, Tulane University, New Orleans, Louisiana.

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GILDEA, JOHN JOSEPH · 2004 to 2020
$31.8M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Visit-to-visit variability of blood pressure and CVD and renal outcomesR01HL110993 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MUNTNER, PAUL · 2012 to 2014
$1.1M
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL110993NHLBI NIH HHS R01 HL117323
6 · The paper itself

Abstract

backgroundThe 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults provides recommendations for the definition of hypertension, systolic and diastolic blood pressure (BP) thresholds for initiation of antihypertensive medication, and BP target goals.

objectivesThis study sought to determine the prevalence of hypertension, implications of recommendations for antihypertensive medication, and prevalence of BP above the treatment goal among U.S. adults using criteria from the 2017 ACC/AHA guideline and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7).

methodsThe authors analyzed data from the 2011 to 2014 National Health and Nutrition Examination Survey (N = 9,623). BP was measured 3 times following a standardized protocol and averaged. Results were weighted to produce U.S. population estimates.

resultsAccording to the 2017 ACC/AHA and JNC7 guidelines, the crude prevalence of hypertension among U.S. adults was 45.6% (95% confidence interval [CI]: 43.6% to 47.6%) and 31.9% (95% CI: 30.1% to 33.7%), respectively, and antihypertensive medication was recommended for 36.2% (95% CI: 34.2% to 38.2%) and 34.3% (95% CI: 32.5% to 36.2%) of U.S. adults, respectively. Nonpharmacological intervention is advised for the 9.4% of U.S. adults with hypertension who are not recommended for antihypertensive medication according to the 2017 ACC/AHA guideline. Among U.S. adults taking antihypertensive medication, 53.4% (95% CI: 49.9% to 56.8%) and 39.0% (95% CI: 36.4% to 41.6%) had BP above the treatment goal according to the 2017 ACC/AHA and JNC7 guidelines, respectively.

conclusionsCompared with the JNC7 guideline, the 2017 ACC/AHA guideline results in a substantial increase in the prevalence of hypertension, a small increase in the percentage of U.S. adults recommended for antihypertensive medication, and more intensive BP lowering for many adults taking antihypertensive medication.

Indexed as

Blood Pressure DeterminationHypertensionAdultAmerican Heart AssociationAntihypertensive AgentsCardiologyHumansNutrition SurveysPatient Care ManagementPatient Care PlanningPractice Guidelines as TopicPrevalenceUnited StatesAntihypertensive Agentshypertensionprevalencetreatment

Identifiers

PMID29146532
PMCPMC5873591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.