ReviewJournal of the American College of Cardiology2017
Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 2.
Review in Journal of the American College of Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03930680 (Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane in Patients With Breast Cancer), which is not on this map. Cited by 156 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane in Patients With Breast Cancer
Who cites it
156 citing papers in PubMed, 4 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- Practical guidance for echocardiography for cancer therapy-related cardiac dysfunction: 2026 focused update.Journal of echocardiography · 2026Guideline
- MRI-derived extracellular volume as a biomarker of cancer therapy cardiotoxicity: systematic review and meta-analysis.European radiology · 2024Pooled it
- Clinical practice guideline of the Interamerican Society of Cardiology on primary prevention of cardiovascular disease in women.Archivos de cardiologia de Mexico · 2022Guideline
- Elevated Cardiac Troponin in Clinical Scenarios Beyond Obstructive Coronary Artery Disease.Medical science monitor : international medical journal of experimental and clinical research · 2019Pooled it
- Cardiac Tamponade Secondary to Anterior Mediastinal Mass: A Cardiology-Centered Approach to Diagnosis and Intervention.JACC. Case reports · 2026Article
- Pericardial Decompression Syndrome Complicated by Left Ventricular Thrombus and Systemic Embolization.JACC. Case reports · 2026Article
- Ischemic heart disease and cardio-onco-hematology: a comprehensive review.Cardio-oncology (London, England) · 2026Review
- Early cardiotoxicity of radiotherapy in breast cancer patients after chemotherapy: the early warning sign.Journal of the Egyptian National Cancer Institute · 2026Observational
- Remote ischemic conditioning protects against anthracycline cardiotoxicity without impairing its antitumor activity.Basic research in cardiology · 2026Article
- Ponatinib confers adult human cardiomyocyte toxicity via inhibition of AKT signaling.Physiological reports · 2026Article
- Article
- Construction of an explainable machine learning model based on SHAP for predicting cardiovascular mortality risk among American cancer survivors.Discover oncology · 2026Article
- Multimodality Imaging in Cardiac Metastasis of Cutaneous Melanoma: Case Report and Systematic Review.Journal of cardiovascular development and disease · 2026Article
- Beyond Hyperglycemia: The Role of Sodium-Glucose Cotransporter 2 Inhibitors in Cancer Treatment-related Cardiac Dysfunction.US cardiology · 2026Review
- Radiation meets inflammation: NLRP3 inflammasome at the core of radiation-induced cardiac injury.Journal of translational medicine · 2025Review
- Longitudinal Patterns of Cardiovascular Disease and Cancer Mortality in Renal Cell Carcinoma Patients by Tumor Stage.JACC. CardioOncology · 2025Article
- Radiation-Induced Cardiac Disease: Dilemma of Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement and Pericardiectomy.JACC. Case reports · 2025Article
- A Comprehensive Review of Radiotherapy-Induced Coronary Artery Disease-Epidemiology, Biological Mechanisms, and Preventive Strategies.International journal of molecular sciences · 2025Review
- Risk factors for early radiation-induced heart damage in patients undergoing pulmonary SBRT.Echo research and practice · 2025Article
- KAT7 contributes to ponatinib-induced hypertension by promoting endothelial senescence and inflammatory responses through activating NF-κB signaling pathway.Journal of hypertension · 2025Article
96 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 1 country.
Funding
Abstract
In this second part of a 2-part review, we will review cancer or cancer therapy-associated systemic and pulmonary hypertension, QT prolongation, arrhythmias, pericardial disease, and radiation-induced cardiotoxicity. This review is based on a MEDLINE search of published data, published clinical guidelines, and best practices in major cancer centers. Newly developed targeted therapy can exert off-target effects causing hypertension, thromboembolism, QT prolongation, and atrial fibrillation. Radiation therapy often accelerates atherosclerosis. Furthermore, radiation can damage the heart valves, the conduction system, and pericardium, which may take years to manifest clinically. Management of pericardial disease in cancer patients also posed clinical challenges. This review highlights the unique opportunity of caring for cancer patients with heart problems caused by cancer or cancer therapy. It is an invitation to action for cardiologists to become familiar with this emerging subspecialty.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.