ArticleHealth and quality of life outcomes2017
Quality of life in children with infantile hemangioma: a case control study.
Article in Health and quality of life outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions for infantile haemangiomas of the skin.The Cochrane database of systematic reviews · 2018Pooled it
- Health-related Quality of Life among Children Living with Rare Diseases in China: a Nationwide Study.Applied research in quality of life · 2026Article
- PHACE syndrome: looking backward and forward.Orphanet journal of rare diseases · 2025Review
- Knowledge, attitudes, and practices on hemangioma among parents of infantile hemangioma patients in South China.Scientific reports · 2025Article
- Malignant and Benign Head and Neck Tumors of the Pediatric Age: A Narrative Review.Current pediatric reviews · 2025Review
- Targeting ESM1 via SOX4 promotes the progression of infantile hemangioma through the PI3K/AKT signaling pathway.Precision clinical medicine · 2024Article
- Mental Health of School-Aged Children Treated with Propranolol or Atenolol for Infantile Hemangioma and Their Parents.Dermatology (Basel, Switzerland) · 2024Article
- Article
- Infantile hemangioma models: is the needle in a haystack?Journal of translational medicine · 2023Review
- Childhood cancer survivorship in China: An overview of the past two decades.Cancer medicine · 2022Review
- Health-Related Quality of Life in Children With Kaposiform Hemangioendothelioma.Frontiers in pediatrics · 2022Article
- Development and validation of psychological status questionnaire for parents of infantile hemangiomas.Translational pediatrics · 2021Article
- Posttraumatic Stress Disorder and executive dysfunction among children and adolescents: A Latent Profile Analysis.International journal of clinical and health psychology : IJCHP · 2019Article
- IADVL SIG Pediatric Dermatology (Academy) Recommendations on Hemangioma of Infancy (HOI).Indian dermatology online journalReview
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundInfantile hemangioma (IH) is the most common vascular tumor in children. It is controversial whether IHs has effects on the quality of life (QOL) in patients of whom IH poses no threat or potential for complication. Thus, we conducted this study to evaluate the q QOL in patients with IH and find the predictors of poor QOL.
methodsThe PedsQL 4.0 Genetic Core Scales and the PedsQL family information form were administered to parents of children with IH and healthy children both younger than 2-year-old. The quality-of-life instrument for IH (IH-QOL) and the PedsQL 4.0 family impact module were administered to parents of children with IH. We compared the PedsQL 4.0 Genetic Core Scales (GCIS) scores of the two groups. Multiple step-wise regression analysis was used to determine factors that influenced QOL in children with IH and their parents.
resultsExcept for physical symptom, we found no significant difference in GCIS between patient group and healthy group (P = 0.409). The internal reliability of IH-QOL was excellent with the Cronbach's alpha coefficient for summary scores being 0.76. Multiple step-wise regression analysis showed that the predictors of poor IH-QOL total scores were hemangioma size, location, and mother's education level. The predictors of poor FIM total scores were hemangioma location and father's education level. The predictors of poor GCIS total scores were children's age, hemangioma location and father's education level.
conclusionThe findings support the feasibility and reliability of the Chinese version of IH-QOL to evaluate the QOL in children with IH and their parents. Hemangioma size, location and education level of mother are important impact factors for QOL in children with IH and their parents.
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