Evidence map›Paper›PMID 29145787›Full record

SynthesisJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2018

Pneumocystosis in dogs: meta-analysis of 43 published cases including clinical signs, diagnostic procedures, and treatment.

Christiane Weissenbacher-Lang, Andrea Fuchs-Baumgartinger, Abigail Guija-De-Arespacochaga, Andrea Klang, Herbert Weissenböck, Frank Künzel

Open access · bronzeAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. A NovelJournal of fungi (Basel, Switzerland) · 2024
    Article
  4. Detection ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  5. Can you BALieve it?Veterinary clinical pathology · 2022
    Article
  6. International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Nested-polymerase chain reaction detection ofSAGE open medical case reports · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christiane Weissenbacher-LangInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
Andrea Fuchs-BaumgartingerInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
Abigail Guija-De-ArespacochagaInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
Andrea KlangInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
Herbert WeissenböckInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
Frank KünzelInstitute of Pathology and Forensic Veterinary Medicine (Weissenbacher-Lang, Fuchs-Baumgartinger, Klang, Weissenböck), University of Veterinary Medicine Vienna, Vienna, Austria.
University of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated 43 published cases of dogs with confirmed Pneumocystis infection regarding the value of clinical parameters indicating the presence of the disease as well as tools for the detection of the pathogen. The assessed parameters included clinical signs, laboratory findings, results of thoracic radiography, autopsy, histopathology, methods for the detection of Pneumocystis, as well as medical therapy. Pneumocystosis was diagnosed most often in certain breeds (Cavalier King Charles Spaniel, Miniature Dachshund) with a predisposition for impaired immunity. The median age of the dogs was 1 y. Chronic therapy-resistant respiratory signs, such as tachypnea, dyspnea, and cough, along with leukocytosis, neutrophilia, and hypogammaglobulinemia, were the most frequently described clinical and clinicopathologic abnormalities. Pneumocystosis can be masked by coinfections with other respiratory pathogens, and the successful detection of Pneumocystis organisms is of major relevance. Several detection methods have been used in the past, but only a few provide reliable results. In 2017, the cytologic evaluation of Giemsa-stained bronchoalveolar lavage samples is generally used, even if sensitivity is only moderate. More reliable results can be achieved using special stains or sensitive molecular techniques. Fast and reliable detection of Pneumocystis is the essential basis for appropriate treatment and higher survival chances for dogs.

Indexed as

Dog DiseasesAnimalsDogsPneumocystisPneumocystis InfectionsClinical signsdiagnosisdogsmeta-analysisPneumocystis cariniitreatment

Identifiers

PMID29145787
PMCPMC6504147
OpenAlexW2770663938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.