ArticleAnnals of the American Thoracic Society2018
Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States.
Article in Annals of the American Thoracic Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 35 citations in OpenAlex.
- Adiposity measures and childhood asthma: one size does not fit all.Pediatric research · 2026Article
- Association of pericoronary fat attenuation index and insulin resistance for the risk of cardiometabolic multimorbidity: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Health Disparities in Pediatric Asthma.Respiratory care · 2025Review
- Association of relative fat mass with asthma: inflammatory markers as potential mediators.Lipids in health and disease · 2025Article
- Chinese expert consensus on the diagnosis, treatment, and management of asthma in women across life.Journal of thoracic disease · 2024Review
- Early-Life Weight Status and Risk of Childhood Asthma or Recurrent Wheeze in Preterm and Term Offspring.The journal of allergy and clinical immunology. In practice · 2023Article
- Large-scale genome-wide association study to identify causal relationships and potential mediators between education and autoimmune diseases.Frontiers in immunology · 2023Article
- Obesity Is Associated with Sustained Symptomatology and Unique Inflammatory Features in Children with Asthma.The journal of allergy and clinical immunology. In practice · 2022Article
- The bidirectional association between wheezing and obesity during adolescence and the beginning of adulthood in the 1993 birth cohort, Pelotas, Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Asthma and obesity: endotoxin another insult to add to injury?Clinical science (London, England : 1979) · 2021Review
- Using Body Composition Groups to Identify Children and Adolescents at Risk of Dyslipidemia.Children (Basel, Switzerland) · 2021Article
- Atopy and pulmonary function among healthy-weight and overweight/obese children with asthma.Pediatric pulmonology · 2021Article
- Risk factors for atopic and nonatopic asthma in Puerto Rican children.Pediatric pulmonology · 2020Article
- Obesity-induced asthma: Role of free fatty acid receptors.The Japanese dental science review · 2019Review
- Obesity and severe asthma.Allergology international : official journal of the Japanese Society of Allergology · 2019Review
- Does Obesity Increase Respiratory Tract Infections in Patients with Asthma?The journal of allergy and clinical immunology. In practice · 2019Observational
- Quantifying the Contribution of Obesity to Incident Childhood Asthma: It's About Time.Pediatrics · 2018Article
- Prevalence and Risk Factors of Asthma and Allergy-Related Diseases among Adolescents (PERFORMANCE) study: rationale and methods.ERJ open research · 2018Article
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5 authors at 2 institutions in 1 country.
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Abstract
rationaleAlthough obesity has been associated with asthma, body mass index is suboptimal to fully characterize adiposity.
objectivesWe examined the relation between adiposity and asthma in a large sample of the U.S. population, using indices defined by dual-energy X-ray absorptiometry.
methodsWe analyzed data from 8,886 children (aged 8-19 yr) and 12,795 adults (aged 20-69 yr) from the 2001 to 2006 National Health and Nutrition Examination Survey. In addition to body mass index, percent body fat, waist circumference, and waist-to-height ratio, dual-energy X-ray absorptiometry was used to calculate whole-body and local adiposity indices: fat mass index; total, trunk, and legs percent fat; and trunk-to-total fat mass ratio, legs-to-total fat mass ratio, and trunk-to-legs fat mass ratios. Logistic regression was used for the analysis of adiposity measures and asthma.
resultsAmong children, general adiposity was significantly associated with asthma, with no major differences by sex. Results were driven by nonatopic children, in whom trunk-predominant (central) adiposity (assessed by waist circumference, waist-to-height ratio, trunk-to-total fat mass ratio, and trunk-to-legs fat mass ratio) was also associated with asthma. There were no significant associations among atopic children. Among adults, all adiposity indices were associated with asthma, with central adiposity significant only among women. The results in adults were driven by atopy, especially in women.
conclusionsAdiposity measured by dual-energy X-ray absorptiometry provides similar information to that obtained by using anthropometric indices among children of both sexes and among adult men. However, dual-energy X-ray absorptiometry provides additional information in adult women, in whom dual-energy X-ray absorptiometry-measured central adiposity is significantly associated with asthma, particularly atopic asthma.
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