ArticleNutrients2017
Dietary Magnesium and Incident Frailty in Older People at Risk for Knee Osteoarthritis: An Eight-Year Longitudinal Study.
Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Mapping Research Trends in Frailty and Nutrition: A Combined Bibliometric and Structured Review (2000-2024).Nutrients · 2025Pooled it
- Magnesium and health outcomes: an umbrella review of systematic reviews and meta-analyses of observational and intervention studies.European journal of nutrition · 2020Pooled it
- The relationship between magnesium and osteoarthritis of knee: A MOOSE guided systematic review and meta-analysis.Medicine · 2019Pooled it
- Review
- Total magnesium intake and risk of frailty in older women.Journal of cachexia, sarcopenia and muscle · 2024Article
- The Integral Role of Magnesium in Muscle Integrity and Aging: A Comprehensive Review.Nutrients · 2023Review
- Association between Elevated Magnesium Intake and Reduced Risk of Recurrent Falls and Frailty in Osteoarthritis: Data from the Osteoarthritis Initiative.The journal of nutrition, health & aging · 2023Article
- Prospective association between dietary magnesium intake and physical performance in older women and men.European journal of nutrition · 2022Article
- Effects of traditional Chinese herb hot compress combined with therapeutic exercise on pain, proprioception, and functional performance among older adults with knee osteoarthritis: A randomized controlled trial.Frontiers in physiology · 2022Article
- MR-PheWAS for the causal effects of serum magnesium on multiple disease outcomes in Caucasian descent.iScience · 2021Article
- The Association between Poor Diet Quality, Physical Fatigability and Physical Function in the Oldest-Old from the Geisinger Rural Aging Study.Geriatrics (Basel, Switzerland) · 2021Article
- The Association between Dietary Magnesium Intake and Magnetic Resonance Parameters for Knee Osteoarthritis.Nutrients · 2019Article
- Angiotensin-Converting Enzyme Inhibitor Use and Incident Frailty: A Longitudinal Cohort Study.Drugs & aging · 2019Article
- Ethnic Differences in Magnesium Intake in U.S. Older Adults: Findings from NHANES 2005⁻2016.Nutrients · 2018Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inadequate magnesium (Mg) intake is associated with lower physical performance, but the relationship with frailty in older people is unclear. Therefore, we aimed to investigate whether higher dietary Mg intake is associated with a lower risk of frailty in a large cohort of North American individuals. Details regarding Mg intake were recorded through a food-frequency questionnaire (FFQ) and categorized as greater than/equal to Recommended Dietary Allowance (RDA) vs. lower. Frailty was defined using the Study of Osteoporotic Fractures index. Multivariable Cox's regression analyses, calculating hazard ratios (HRs) with 95% confidence intervals (CIs), were undertaken by sex. In total, 4421 individuals with knee osteoarthritis or who were at high risk without frailty at baseline (mean age: 61.3, females = 58.0%) were followed for 8 years. After adjusting for 11 potential baseline confounders, reaching the RDA for Mg lowered risk of frailty among men (total
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