ReviewCurrent treatment options in oncology2017
Combined Vertebral Augmentation and Radiofrequency Ablation in the Management of Spinal Metastases: an Update.
Review in Current treatment options in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 66 citations in OpenAlex.
- Trends and hotspots in the studies of spinal metastasis: A bibliometric analysis from 2000 to 2023.Medicine · 2026Review
- Ablative Techniques for the Management of Osseous Spine Metastases: A Narrative Review.Journal of clinical medicine · 2025Review
- The Missing Link: Integrating Interventional Pain Management in the Era of Multimodal Oncology.Pain and therapy · 2025Review
- Minimally invasive interventional guided imaging therapies of musculoskeletal tumors.Quantitative imaging in medicine and surgery · 2024Review
- Complication avoidance, rehabilitation, pain therapy and palliative care for patients with metastatic spine tumors: WFNS spine committee recommendations.Neurosurgical review · 2024Review
- Electrochemotherapy in Spine Metastases: A Case Series Focused on Technical Aspects, Surgical Strategies and Results.Diagnostics (Basel, Switzerland) · 2024Article
- The use of interventional procedures for cancer pain. A brief review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Review
- Cementoplasty to cryoablation: review and current status.BJR open · 2024Review
- Infrapedicular approach to CT-guided thermal ablation in the thoracic spine.The neuroradiology journal · 2022Article
- Treatment of Metastatic Spinal Disease; what the Radiologist needs to know.The British journal of radiology · 2022Review
- State-of-the-art of minimally invasive treatments of bone metastases.Journal of bone oncology · 2022Review
- A Retrospective Evaluation of Operative and Postoperative Outcomes in Patients with Spinal Metastases from a Single Center to Compare Vertebrectomy with Combined Vertebrectomy and Radiofrequency Ablation.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Radiofrequency ablation and balloon kyphoplasty for palliation of painful spinal metastases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
- Clinical effectiveness of percutaneous vertebroplasty in conjunction with postoperative radiotherapy in the treatment of spinal metastases.Journal of cancer research and clinical oncology · 2021Article
- Comparison of post-operative pain scores and opioid use between kyphoplasty and radiofrequency ablation (RFA) systems combined with cement augmentation.Skeletal radiology · 2020Article
- Cooled radiofrequency ablation technology for painful bone tumors.Acta bio-medica : Atenei Parmensis · 2020Article
- The clinical utility of the Spinal Instability Neoplastic Score (SINS) system in spinal epidural metastases: a retrospective study.Spinal cord · 2020Article
- Posterior Decompression Surgery and Radiofrequency Ablation Followed by Vertebroplasty in Spinal Metastases from Lung Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Metastatic Melanoma Epidural Tumour Regression Following Percutaneous Radiofrequency Ablation.Cureus · 2020Article
- Ablation, consolidation and radiotherapy for the management of metastatic lesions of the spine: impact on the quality of life in a mid-term clinical and diagnostic follow-up in a pilot study.Medical oncology (Northwood, London, England) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementSpinal metastases are the most commonly encountered tumour of the spine, occurring in up to 40% of patients with cancer. Each year, approximately 5% of cancer patients will develop spinal metastases. This number is expected to increase as the life expectancy of cancer patients increases. Patients with spinal metastases experience severe and frequently debilitating pain, which often decreases their remaining quality of life. With a median survival of less than 1 year, the goals of treatment in spinal metastases are reducing pain, improving or maintaining level of function and providing mechanical stability. Currently, conventional treatment strategies involve a combination of analgesics, bisphosphonates, radiotherapy and/or relatively extensive surgery. Despite these measures, pain management in patients with spinal metastases is often suboptimal. In the last two decades, minimally invasive percutaneous interventional radiology techniques such as vertebral augmentation and radiofrequency ablation (RFA) have shown progressive success in reducing pain and improving function in many patients with symptomatic spinal metastases. Both vertebral augmentation and RFA are increasingly being recognised as excellent alternative to medical and surgical management in carefully selected patients with spinal metastases, namely those with severe refractory pain limiting daily activities and stable pathological vertebral compression fractures. In addition, for more complicated lesions such as spinal metastasis with soft tissue extension, combined treatments such as vertebral augmentation in conjunction with RFA may be helpful. While combined RFA and vertebral augmentation have theoretical benefits, comparative trials have not been performed to establish superiority of combined therapy. We believe that a multidisciplinary approach as well as careful pre-procedure evaluation and imaging will be necessary for effective and safe management of spinal metastases. RFA and vertebral augmentation should be considered during early stages of the disease so as to maintain the remaining quality of life in this patient population group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.