Evidence map›Paper›PMID 29143676›Full record

ReviewBMC infectious diseases2017

The future of viral hepatitis testing: innovations in testing technologies and approaches.

Rosanna W Peeling, Debrah I Boeras, Francesco Marinucci, Philippa Easterbrook

Open access · goldAbstract readReview
In one paragraph

Review in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 128 citations in OpenAlex.

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  20. National viral hepatitis control program in India: Call for update.Journal of family medicine and primary care · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rosanna W PeelingDepart of Clinical Research and International Diagnostics Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Rosanna.peeling@lshtm.ac.uk.
Debrah I BoerasDepart of Clinical Research and International Diagnostics Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Francesco MarinucciFoundation for Innovative New Diagnostics, Geneva, Switzerland.
Philippa EasterbrookGlobal Hepatitis Programme, HIV Department, World Health Organization, Geneva, Switzerland.
University of London · GBFoundation for Innovative New Diagnostics · CHWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

A large burden of undiagnosed hepatitis virus cases remains globally. Despite the 257 million people living with chronic hepatitis B virus infection, and 71 million with chronic viraemic HCV infection, most people with hepatitis remain unaware of their infection. Advances in rapid detection technology have created new opportunities for enhancing access to testing and care, as well as monitoring of treatment. This article examines a range of other technological innovations that can be leveraged to provide more affordable and simplified approaches to testing for HBV and HCV infection and monitoring of treatment response. These include improved access to testing through alternative sampling methods (use of dried blood spots, oral fluids, self-testing) and combination rapid diagnostic tests for detection of HIV, HBV and HCV infection; more affordable options for confirmation of virological infection (HBV DNA and HCV RNA) such as point-of-care molecular assays, HCV core antigen and multi-disease polyvalent molecular platforms that make use of existing centralised laboratory based or decentralised TB and HIV instrumentation for viral hepatitis testing; and finally health system improvements such as integration of laboratory services for procurement and sample transportation and enhanced data connectivity to support quality assurance and supply chain management.

Indexed as

Point-of-Care SystemsBody FluidsDried Blood Spot TestingHepatitis BHepatitis CHepatitis, Viral, HumanHumansNucleic AcidsSerologic TestsNucleic AcidsDiagnostic testHepatitis B virusHepatitis C virusInnovationsLow resource settingsPoint-of-careWHO

Identifiers

PMID29143676
PMCPMC5688478
OpenAlexW2765202013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.