Evidence map›Paper›PMID 29143670›Full record

SynthesisBMC genomics2017

Genes to predict VO

Camilla J Williams, Mark G Williams, Nir Eynon, Kevin J Ashton, Jonathan P Little, Ulrik Wisloff, Jeff S Coombes

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 4 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 4 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. A Systematic Review and Meta-analysis Highlights a Link Between Aerobic Fitness and Telomere Maintenance.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Pooled it
  2. Pooled it
  3. A review of the ketogenic diet for endurance athletes: performance enhancer or placebo effect?Journal of the International Society of Sports Nutrition · 2020
    Pooled it
  4. Effects of Ashwagandha (Nutrients · 2020
    Pooled it
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  15. Genes · 2025
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  19. Review
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Camilla J WilliamsCentre for Research on Exercise, Physical Activity and Health (CRExPAH), School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Mark G WilliamsMolecular Genetics Department, Mater Pathology, South Brisbane, Queensland, Australia.
Nir EynonInstitute of Sport, Exercise and Active Living (ISEAL), Victoria University, Melbourne, 8001, Australia. Nir.Eynon@vu.edu.au.
Kevin J AshtonFaculty of Health Sciences and Medicine, Bond University, Robina, Queensland, Australia.
Jonathan P LittleSchool of Health and Exercise Sciences, University of British Columbia, Okanagan, Canada.
Ulrik WisloffCentre for Research on Exercise, Physical Activity and Health (CRExPAH), School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.
Jeff S CoombesCentre for Research on Exercise, Physical Activity and Health (CRExPAH), School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, Queensland, Australia.
The University of Queensland · AUBond University · AUMater Health Services · AUNorwegian University of Science and Technology · NOUniversity of British Columbia · CAVictoria University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiorespiratory fitness (VO

methodsPeer-reviewed research papers published up until October 2016 from four databases were examined. Articles were included if they examined genetic variants, incorporated a supervised aerobic exercise intervention; and measured VO

resultsThirty-five articles describing 15 cohorts met the criteria for inclusion. The majority of studies used a cross-sectional retrospective design. Thirty-two studies researched candidate genes, two used Genome-Wide Association Studies (GWAS), and one examined mRNA gene expression data, in addition to a GWAS. Across these studies, 97 genes to predict VO

conclusionNinety-seven genes have been identified as possible predictors of VO

Indexed as

Cardiorespiratory FitnessExerciseGenotyping TechniquesHumansOxygen ConsumptionCardiorespiratory fitnessPredictor genesTrainingVO2max

Identifiers

PMID29143670
PMCPMC5688475
OpenAlexW2770750538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.