Evidence map›Paper›PMID 29143596›Full record

ArticleBMC genomics2017

Genetic testing for exercise prescription and injury prevention: AIS-Athlome consortium-FIMS joint statement.

Nicole Vlahovich, David C Hughes, Lyn R Griffiths, Guan Wang, Yannis P Pitsiladis, Fabio Pigozzi, Nobert Bachl, Nir Eynon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Testing in Football: A Narrative Review.Sports (Basel, Switzerland) · 2024
    Review
  7. Review
  8. Review
  9. Sweating it out: How physical activity can combat high genetic risk for nonalcoholic fatty liver disease.Liver international : official journal of the International Association for the Study of the Liver · 2023
    Article
  10. New Opportunities to Advance the Field of Sports Nutrition.Frontiers in sports and active living · 2022
    Review
  11. Article
  12. Genetic test for the personalization of sport training.Acta bio-medica : Atenei Parmensis · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Nicole VlahovichAustralian Institute of Sport (AIS), Australian Sports Commission, Canberra, Australia.
David C HughesAustralian Institute of Sport (AIS), Australian Sports Commission, Canberra, Australia.
Lyn R GriffithsGenomics Research Centre, Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology, Brisbane, Australia.
Guan WangReference Collaborating Centre of Sports Medicine for Anti-Doping Research, University of Brighton, Eastbourne, UK.
Yannis P PitsiladisReference Collaborating Centre of Sports Medicine for Anti-Doping Research, University of Brighton, Eastbourne, UK.
Fabio PigozziDepartment of Movement Human and Health Sciences University of Rome "Foro Italico", Rome, Italy.
Nobert BachlInternational Federation of Sports Medicine (FIMS), Lausanne, Switzerland.
Nir EynonInstitute of Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, PO Box 14428, Melbourne, VIC, 8001, Australia. Nir.Eynon@vu.edu.au.
Australian Sports Commission · AUInternational Federation of Sports Medicine · CHQueensland University of Technology · AUUniversity of Brighton · GBUniversity of Vienna · ATVictoria University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been considerable growth in basic knowledge and understanding of how genes are influencing response to exercise training and predisposition to injuries and chronic diseases. On the basis of this knowledge, clinical genetic tests may in the future allow the personalisation and optimisation of physical activity, thus providing an avenue for increased efficiency of exercise prescription for health and disease.

resultsThis review provides an overview of the current status of genetic testing for the purposes of exercise prescription and injury prevention. As such there are a variety of potential uses for genetic testing, including identification of risks associated with participation in sport and understanding individual response to particular types of exercise. However, there are many challenges remaining before genetic testing has evidence-based practical applications; including adoption of international standards for genomics research, as well as resistance against the agendas driven by direct-to-consumer genetic testing companies. Here we propose a way forward to develop an evidence-based approach to support genetic testing for exercise prescription and injury prevention.

conclusionBased on current knowledge, there is no current clinical application for genetic testing in the area of exercise prescription and injury prevention, however the necessary steps are outlined for the development of evidence-based clinical applications involving genetic testing.

Indexed as

ExerciseGenetic TestingBone and BonesClustered Regularly Interspaced Short Palindromic RepeatsEvidence-Based MedicineHumansMusclesWounds and Injuries

Identifiers

PMID29143596
PMCPMC5688405
OpenAlexW2771044587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.