ArticleNeurogastroenterology and motility2018
Identification of swallowing disorders in early and mid-stage Parkinson's disease using pattern recognition of pharyngeal high-resolution manometry data.
Article in Neurogastroenterology and motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- A comprehensive review of the diagnosis and treatment of Parkinson's disease dysphagia and aspiration.Expert review of gastroenterology & hepatology · 2020Pooled it
- Pressure and Timing Differences Between Volitional and Non-Cued Saliva Swallows Measured with Pharyngeal High-Resolution Manometry.Dysphagia · 2026Article
- Association between Perceived Dysphagia Symptoms and Swallowing Physiology in Parkinson's Disease.Movement disorders clinical practice · 2025Article
- Article
- Normative High-Resolution Pharyngeal Manometry: Impact of Age, Size of System, and Sex on Primary Metrics and Pressure Stability.Dysphagia · 2024Article
- Parkinson's disease is associated with low striated esophagus contractility potentially contributing to the development of dysphagia.Neurogastroenterology and motility · 2024Article
- Variability in quantitative outcomes of instrumental swallowing assessments in adults: a scoping review.CoDAS · 2024Article
- AI-Based Detection of Aspiration for Video-Endoscopy with Visual Aids in Meaningful Frames to Interpret the Model Outcome.Sensors (Basel, Switzerland) · 2022Article
- A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value.Journal of neurology · 2022Review
- Pharyngeal Pressure Variability During Volitional Swallowing Maneuvers.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Application of Deep Learning Models for Automated Identification of Parkinson's Disease: A Review (2011-2021).Sensors (Basel, Switzerland) · 2021Review
- Swallowing Assessment in Parkinson's Disease: Patient and Investigator Reported Outcome Measures are not Aligned.Dysphagia · 2021Article
- The Frequency of Atypical and Extreme Values for Pharyngeal Phase Swallowing Measures in Mild Parkinson Disease Compared to Healthy Aging.Journal of speech, language, and hearing research : JSLHR · 2021Article
- Parkinson disease and the gut: new insights into pathogenesis and clinical relevance.Nature reviews. Gastroenterology & hepatology · 2020Review
- Article
- Review
- Artificial Intelligence Applied to Gastrointestinal Diagnostics: A Review.Journal of pediatric gastroenterology and nutrition · 2020Review
- Management of Dysphagia in Acquired and Progressive Neurologic Conditions.Seminars in speech and language · 2019Review
- Parkinson's Disease and Current Treatments for Its Gastrointestinal Neurogastromotility Effects.Current treatment options in gastroenterology · 2018Review
- Methods for measuring swallowing pressure variability using high-resolution manometry.Frontiers in applied mathematics and statistics · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundParkinson's disease (PD) can cause severe dysphagia, especially later in disease progression. Early identification of swallowing dysfunction may lead to earlier intervention. Pharyngeal high-resolution manometry (HRM) provides complementary information to videofluoroscopy, with advantages of being quantitative and objective. Artificial neural network (ANN) classification can examine non-linear relationships among multiple variables with relatively low bias. We evaluated if ANN techniques could differentiate between patients with PD and healthy controls.
methodsSimultaneous videofluoroscopy and pharyngeal HRM were performed on 31 patients with early to mid-stage PD and 31 age- and sex-matched controls during thin-liquid swallows of 2 cc, 10 cc and comfortable sip volume. We performed multilayer-perceptron analyses on only videofluoroscopic data, only HRM data or a combination of the two. We also evaluated variability-based parameters, representing variability in manometric parameters across multiple swallows. We hypothesized that patients with PD and controls would be classified with at least 80% accuracy, and that combined videofluoroscopic and HRM data would classify participants better than either alone. KEY
resultsClassification rates were highest with all parameters considered. Maximum classification rate was 82.3 ± 5.2%, recorded for 2 cc swallows. Inclusion of variability-based parameters improved classification rates. Classification rates using only manometric parameters were similar to those using all parameters, and rates were substantially lower for the comfortable sip volumes. CONCLUSIONS & INFERENCES: Results from these classifications highlight the differences between swallowing function in patients with early and mid-stage PD and healthy controls. Early identification of swallowing dysfunction is key to developing preventative swallowing treatments for those with PD.
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