Evidence map›Paper›PMID 29143408›Full record

ArticleJournal of labelled compounds & radiopharmaceuticals2018

Automated synthesis of PET radiotracers by copper-mediated

Andrew V Mossine, Allen F Brooks, Vadim Bernard-Gauthier, Justin J Bailey, Naoko Ichiishi, Ralf Schirrmacher, Melanie S Sanford, Peter J H Scott

Open access · bronzeAbstract read
In one paragraph

Article in Journal of labelled compounds & radiopharmaceuticals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 54 citations in OpenAlex.

  1. Chemical science · 2026
    Article
  2. Illuminating proinflammatory myeloid cells with PET tracers targeting GPR84.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Simple and Efficient Synthesis ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Dosimetry of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  14. Journal of medicinal chemistry · 2023
    Article
  15. Strategies for the Production of [Organic process research & development · 2023
    Article
  16. Article
  17. Optimization of Direct AromaticMolecules (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Exploration of alcohol-enhanced Cu-mediated radiofluorination toward practical labeling.Journal of labelled compounds & radiopharmaceuticals · 2022
    Article
  20. SThe Journal of organic chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Andrew V MossineDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Allen F BrooksDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Vadim Bernard-GauthierMedical Isotope and Cyclotron Facility, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada.
Justin J BaileyMedical Isotope and Cyclotron Facility, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada.
Naoko IchiishiDepartment of Chemistry, University of Michigan, Ann Arbor, MI, USA.
Ralf SchirrmacherMedical Isotope and Cyclotron Facility, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada.
Melanie S SanfordDepartment of Chemistry, University of Michigan, Ann Arbor, MI, USA.
Peter J H ScottDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0002-6505-0450
University of Michigan · USUniversity of Alberta · CA

Funding

Synthesis of Novel PET Radiotracers for Imaging in Alzheimer’s Disease and Related DisordersR01EB021155 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S., SCOTT, PETER JAMES HENRY · 2016 to 2024
$3.2M
NIBIB NIH HHS R01 EB021155
6 · The paper itself

Abstract

In this paper, we describe the use of Cu-mediated [

Indexed as

AutomationBoronCopperFluorine RadioisotopesImidazolesLigandsPositron-Emission TomographyPyridazinesRadiopharmaceuticalsReceptor, trkBReceptor, trkCBoronCopperFluorine RadioisotopesImidazolesLigandsPyridazinesRadiopharmaceuticalsReceptor, trkBReceptor, trkCautomated radiosynthesisautomationF18fluorine-18late-stage fluorinationPET chemistryradiochemistry

Identifiers

PMID29143408
PMCPMC5896751
OpenAlexW2769121948

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.