Evidence map›Paper›PMID 29143159›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2018

Six-year outcome in subjects diagnosed with attention-deficit/hyperactivity disorder as adults.

Dan Edvinsson, Lisa Ekselius

Abstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Health-related quality of life in psychiatric outpatients: a cross-sectional study of associations with symptoms, diagnoses, and employment status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  5. Article
  6. The course of attention-deficit/hyperactivity disorder through midlife.European archives of psychiatry and clinical neuroscience · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Five-year outcomes of ADHD diagnosed in adulthood.Scandinavian journal of psychology · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dan EdvinssonDepartment of Neuroscience, Psychiatry, Uppsala University, Uppsala University Hospital, Uppsala, Sweden.
Lisa EkseliusDepartment of Neuroscience, Psychiatry, Uppsala University, Uppsala University Hospital, Uppsala, Sweden. lisa.ekselius@neuro.uu.se.ORCID http://orcid.org/0000-0002-5760-7730

Funding

Swedish Research Council Dnr 2003-2253
6 · The paper itself

Abstract

There are very few studies on the long-term outcome in subjects diagnosed with ADHD as adults. The objective of the present study was to assess this and relate the outcome to whether there was current medication or not and to other potential predictors of favourable outcome. A prospective clinical cohort of adults diagnosed with ADHD according to DSM-IV criteria was followed-up on an average of 6 years after first evaluation (n = 124; mean age 42 years, 51% males). ADHD symptom trajectories were assessed as well as medication, global functioning, disability, health-related quality of life, and alcohol and drug consumption at follow-up. Ninety percent of those diagnosed were initially treated pharmacologically and half of them discontinued treatment. One-third reported remission, defined as not fulfilling any ADHD subtype and a GAF-value last year ≥ 70, which was not affected by comorbidity at baseline. Current medication was not associated with remission. Subjects evaluated and first diagnosed with ADHD as adults are functionally improved at follow-up 6 years later despite a high percentage of psychiatric comorbidity at baseline. Half dropped out of medication, and there was no difference in ADHD remission between subjects with on-going medication at follow-up or subjects without medication, although current medication was related to a higher degree of self-reported global improvement.

Indexed as

Treatment OutcomeAdultAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMethylphenidateMiddle AgedOutcome Assessment, Health CareOutpatientsPsychiatric Status Rating ScalesQuality of LifeSurveys and QuestionnairesCentral Nervous System StimulantsMethylphenidateADHDAdultOutcomePharmacotherapyResponse

Identifiers

PMID29143159
PMCPMC5956008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.