Evidence map›Paper›PMID 29142997›Full record

ArticleBiomaterials science2017

Advanced smart-photosensitizers for more effective cancer treatment.

Wooram Park, Soojeong Cho, Jieun Han, Heejun Shin, Kun Na, Byeongdu Lee, Dong-Hyun Kim

Open access · greenAbstract read
In one paragraph

Article in Biomaterials science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 103 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Cellular Mechanisms of Singlet Oxygen in Photodynamic Therapy.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Triggering Immune System With Nanomaterials for Cancer Immunotherapy.Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Tailor-Made Nanomaterials for Diagnosis and Therapy of Pancreatic Ductal Adenocarcinoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  17. Article
  18. Review
  19. Bacterial eliminationNanoscale advances · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Wooram ParkDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. dhkim@northwestern.edu.
Soojeong Cho
Jieun Han
Heejun Shin
Kun Na
Byeongdu Lee
Dong-Hyun Kim
Government of the Republic of Korea · KRNorthwestern University · USArgonne National Laboratory · US

Funding

Magnetic Nanocomposites for Catheter-Directed Drug Delivery to Liver TumorsR21EB017986 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2014 to 2015
$425k
Magnetic Micelles for Catheter-Directed Sorafenib Delivery to Liver TumorsR21CA185274 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2015 to 2016
$367k
Targeted Transcatheter Magneto-Mechanical Therapy for Hepatocellular CarcinomaR21CA173491 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2013 to 2014
$364k
NCI NIH HHS R21 CA173491NCI NIH HHS R21 CA185274NIBIB NIH HHS R21 EB017986
6 · The paper itself

Abstract

Photodynamic therapy (PDT) based upon the use of light and photosensitizers (PSs) has been used as a novel treatment approach for a variety of tumors. It, however, has several major limitations in the clinic: poor water solubility, long-term phototoxicity, low tumor targeting efficacy, and limited light penetration. With advances in nanotechnology, materials science, and clinical interventional imaging procedures, various smart-PSs have been developed for improving their cancer-therapeutic efficacy while reducing the adverse effects. Here, we briefly review state-of-the-art smart-PSs and discuss the future directions of PDT technology.

Indexed as

HumansNanotechnologyNeoplasmsPhotochemotherapyPhotosensitizing AgentsPhotosensitizing Agents

Identifiers

PMID29142997
PMCPMC5736440
OpenAlexW2766987113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.