Evidence map›Paper›PMID 29142969›Full record

ArticleKidney international reports2017

Elucidation of Renal Scars in Children With Vesicoureteral Reflux Using Contrast-Enhanced Ultrasound: A Pilot Study.

David S Hains, Harris L Cohen, M Beth McCarville, Ellen E Ellison, Amy Huffman, Stacey Glass, Aslam H Qureshi, Keith R Pierce, Ashlyn L Cahill, Ashley Dixon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

David S HainsCenter for Innate Immunity Translational Research, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Harris L CohenDepartment of Radiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
M Beth McCarvilleDepartment of Diagnostic Imaging (MS 220), St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Ellen E EllisonDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Amy HuffmanDepartment of Radiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Stacey GlassDepartment of Radiology, Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Aslam H QureshiCenter for Innate Immunity Translational Research, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Keith R PierceCenter for Innate Immunity Translational Research, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Ashlyn L CahillCenter for Innate Immunity Translational Research, Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
Ashley DixonDepartment of Urology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Noel Delos SantosDepartment of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
University of Tennessee Health Science Center · USLe Bonheur Children's Hospital · USSt. Jude Children's Research Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVesicoureteral reflux is a common disorder in children but can result in kidney scarring following acute pyelonephritis. The gold standard diagnostic to detect renal scars in children is

methodsIn this study, we performed CEUS in 7 children with documented renal scars by radiographic imaging consistent with reflux nephropathy.

resultsIn all subjects, CEUS detected all previously known radiologic abnormalities as well as detecting new areas of hypoenhancing renal parenchyma. None of the patients experienced any serious adverse events. DISCUSSION: This study represents the first report of using CEUS to characterize renal scars in children with reflux nephropathy. We conclude that CEUS is a highly sensitive, rapid, and cost-effective diagnostic imaging modality for detecting and monitoring renal scars in children with vesicoureteral reflux.

Indexed as

contrast-enhanced ultrasoundreflux nephropathyvesicoureteral reflux

Identifiers

PMID29142969
PMCPMC5678645
OpenAlexW2581744883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.